Janneth Gonzalez

TL;DR: Data suggest that protective effects of tibolone against lipotoxicity may be mediated, in part, through modulation of the different cellular mechanisms of astrocytes.

TL;DR: This review evaluates some of the most relevant models of astrocyte metabolism, including genome-scale reconstructions and astroCyte-neuron interactions developed in the last few years, and discusses novel strategies from the multi-omics perspective and computational models of other glial cell types that will increase knowledge in brain metabolism and its association with neurodegenerative diseases.

TL;DR: The three dimensional model of Leishmania RPA-1 serves as a starting point for both functional analysis and its exploration as a chemotherapeutic target to combat leishmaniasis, and shows affinity in vitro for the HSP70 mRNA metabolism.

TL;DR: In this article , the authors collected information regarding proteins from SARS-CoV-2 and humans and how these proteins interact and represented this data as networks that allow them to gain insights into protein-protein interactions between both organisms.

TL;DR: The results showed eight new key common residues between the studied neurotoxins interacting with a histidine ring and the selectivity filter of the receptor, thus showing a possible pattern of interaction.