Janneth Gonzalez

TL;DR: How these events affect astrocytes response to these chronic neuropathologies, such as Alzheimer’s AD and Parkinson ́s PD diseases, Amyotrophic Lateral Syndrome (ALS), and Multiple Sclerosis is discussed.

TL;DR: Parkinson Disease is the second most chronic neurodegenerative disorder in the world, after Alzheimer s Disease, and is estimated to affect about 1% of the population over 60 years of age.

TL;DR: Regulation of brain inflammation combined with the recovery of fundamental cellular aspects in the face of injury makes CM-hMSCA a promising candidate for the protection of astrocytes in brain pathologies.

TL;DR: This is the first global high-quality, manually curated metabolic reconstruction network of a human astrocyte, and it is shown that the obtained flux distributions in the model, are in accordance with literature-based findings.

TL;DR: The main aim of this work is to study the effects of birth hypothermia on the actin cytoskeleton of neostriatal post-synaptic densities (PSD) in 60 days olds rats by immunohistochemistry, photooxidation and western blot, suggesting that the decrease of the body temperature decreases the act in modifications in dendritic spines preventing the neuronal death.