J
Jason W. H. Wong
Researcher at Li Ka Shing Faculty of Medicine, University of Hong Kong
Publications - 189
Citations - 8329
Jason W. H. Wong is an academic researcher from Li Ka Shing Faculty of Medicine, University of Hong Kong. The author has contributed to research in topics: Gene & Cancer. The author has an hindex of 46, co-authored 175 publications receiving 7382 citations. Previous affiliations of Jason W. H. Wong include University of New South Wales & University College Dublin.
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Journal ArticleDOI
Surgical management of benign oesophago‐pleural fistula
TL;DR: Although all three patients recovered, the morbidity was considerable and they were subjected to surgery after the infection had been brought under control.
Journal ArticleDOI
Repurposing Azacitidine and Carboplatin to Prime Immune Checkpoint Blockade–resistant Melanoma for Anti-PD-L1 Rechallenge
A. van der Westhuizen,Megan Lyle,Moira C. Graves,Xiaoqiang Zhu,Jason W. H. Wong,Kerrie Cornall,Shuwen Ren,Leanna Pugliese,Richard S. Levy,Adeeb J Majid,Ricardo E. Vilain,Nikola A. Bowden +11 more
TL;DR: Investigation of an early phase II study of azacitidine and carboplatin priming for anti-PDL1 immunotherapy in patients with advanced ICB-resistant melanoma found it can induce disease stabilization and re-sensitisation to ICB for metastatic melanoma.
Journal ArticleDOI
Pyloroplasty in gastric replacement of the esophagus after esophagectomy: one-layer or two-layer technique?: Surgical technique in pyloroplasty
Posted ContentDOI
XPD protects CTCF-Cohesin binding sites from somatic mutagenesis
Jayne A. Barbour,Tong Ou,Hu Fang,Noel Yue,Xiaoqiang Zhu,Michelle W. Wong-Brown,Haocheng Yang,Yuen T. Wong,Nikola A. Bowden,Song Wu,Jason W. H. Wong +10 more
TL;DR: Analysis of XPD occupancy and CBS hotspot mutations in other cancer types suggest that XPD protects CBS from DNA damage, and implicates XPD in genomic integrity maintenance at topologically-associating domain boundaries marked by CTCF-cohesin binding.
Posted ContentDOI
Cell Type-Specific Regulation by a Heptad of Transcription Factors in Human Hematopoietic Stem and Progenitor Cells
Shruthi Subramanian,Julie A. I. Thoms,Yizhou Huang,Paola Cornejo,Sebastien Jacquelin,Sylvie Shen,Emma Song,Swapna Joshi,Chris Brownlee,Petter S. Woll,Diego Chacon Fajardo,Dominik Beck,David J. Curtis,Kenneth Yehson,Vicki Antonenas,Tracey O' Brien,Annette Trickett,Jason A. Powell,Ian D. Lewis,Stuart M. Pitson,Maher K. Gandhi,Steven W. Lane,Fatemeh Vafaee,Emily S. W. Wong,Berthold Göttgens,Hamid Alinejad Rokny,Jason W. H. Wong,John E. Pimanda +27 more
TL;DR: In this article , the authors mapped genome-wide chromatin contacts and TF binding profiles in HSPC subsets (HSC, CMP, GMP, MEP) and found that heptad occupancy and enhancer-promoter interactions varied significantly across cell types and were associated with cell-type-specific gene expression.