J
Jason W. H. Wong
Researcher at Li Ka Shing Faculty of Medicine, University of Hong Kong
Publications - 189
Citations - 8329
Jason W. H. Wong is an academic researcher from Li Ka Shing Faculty of Medicine, University of Hong Kong. The author has contributed to research in topics: Gene & Cancer. The author has an hindex of 46, co-authored 175 publications receiving 7382 citations. Previous affiliations of Jason W. H. Wong include University of New South Wales & University College Dublin.
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Journal ArticleDOI
Control of mature protein function by allosteric disulfide bonds.
TL;DR: Allosteric disulfides identified to date all link β-strands or β-loops, and how they control the activity of the respective proteins are discussed.
Journal ArticleDOI
Epigenetic inactivation of the candidate tumor suppressor USP44 is a frequent and early event in colorectal neoplasia
Mathew A. Sloane,Jason W. H. Wong,Dilmi Perera,Andrea Nuñez,John E. Pimanda,Nicholas J. Hawkins,Oliver M. Sieber,Michael J. Bourke,Luke B. Hesson,Robyn L. Ward +9 more
TL;DR: The data shows that USP44 is epigenetically inactivated in colorectal adenomas, but this alone is not sufficient to cause aneuploidy in colOREctal neoplasia.
Journal ArticleDOI
Squamous cell carcinoma and adenocarcinoma of the lower third of the esophagus and gastric cardia: Similarities and differences
Andreas Alexandrou,Peter A. Davis,Simon Law,Sudish C. Murthy,Brian P. Whooley,Jason W. H. Wong +5 more
TL;DR: Squamous cell carcinoma of the lower esophagus and ADC of the cardia differed in patient demographics and clinical features but long-term prognoses were similar.
Journal ArticleDOI
Objective assessment of technical skills of surgical trainees in Hong Kong
TL;DR: The applicability of these assessment tools to trainees with a different training background in another country was examined.
Journal ArticleDOI
PDGF-AB and 5-Azacytidine induce conversion of somatic cells into tissue-regenerative multipotent stem cells
Vashe Chandrakanthan,Avani Yeola,Jair C. Kwan,Rema A. Oliver,Qiao Qiao,Young Chan Kang,Peter Zarzour,Dominik Beck,Lies Boelen,Ashwin Unnikrishnan,Jeanette E. Villanueva,Andrea Nuñez,Kathy Knezevic,Cintia Palu,Rabab Nasrallah,Michael Carnell,Alexander Macmillan,Renee Whan,Yan Yu,Philip Hardy,Shane T. Grey,Amadeus Gladbach,Fabien Delerue,Lars M. Ittner,Lars M. Ittner,Ralph J. Mobbs,Carl R. Walkley,Louise E. Purton,Robyn L. Ward,Jason W. H. Wong,Luke B. Hesson,William R. Walsh,John E. Pimanda +32 more
TL;DR: It is reported that transient treatment with AZA in combination with platelet-derived growth factor–AB converts primary somatic cells into tissue-regenerative multipotent stem (iMS) cells, a vector-free method of generating iMS cells from primary terminally differentiated cells has significant scope for application in tissue regeneration.