J
Jaume Martorell
Researcher at University of Barcelona
Publications - 60
Citations - 2887
Jaume Martorell is an academic researcher from University of Barcelona. The author has contributed to research in topics: Transplantation & Kidney transplantation. The author has an hindex of 21, co-authored 60 publications receiving 2747 citations.
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Journal ArticleDOI
Clinical transplantation of a tissue-engineered airway
Paolo Macchiarini,Philipp Jungebluth,Tetsuhiko Go,M. Adelaide Asnaghi,Louisa E.N. Rees,Tristan A Cogan,A. Dodson,Jaume Martorell,Silvia Bellini,Pier Paolo Parnigotto,Sally C. Dickinson,Anthony P. Hollander,Sara Mantero,Maria Teresa Conconi,Martin A. Birchall +14 more
TL;DR: The results show that a cellular, tissue-engineered airway with mechanical properties that allow normal functioning, and which is free from the risks of rejection, is produced, suggesting that autologous cells combined with appropriate biomaterials might provide successful treatment for patients with serious clinical disorders.
Journal ArticleDOI
Both epithelial cells and mesenchymal stem cell-derived chondrocytes contribute to the survival of tissue-engineered airway transplants in pigs.
Tetsuhiko Go,Philipp Jungebluth,Silvia Baiguero,Adelaide Asnaghi,Jaume Martorell,Helmut Ostertag,Sara Mantero,Martin A. Birchall,Augustinus Bader,Paolo Macchiarini +9 more
TL;DR: It is suggested that the seeding of both epithelial and mesenchymal stem cell-derived chondrocytes is necessary for optimal graft survival, and the clinical potential of autologous cell- and tissue-engineered tracheal grafts is confirmed.
Journal ArticleDOI
Structural and morphologic evaluation of a novel detergent-enzymatic tissue-engineered tracheal tubular matrix.
Philipp Jungebluth,Tetsuhiko Go,Adelaide Asnaghi,Silvia Bellini,Jaume Martorell,Chiara Calore,Luca Urbani,Helmut Ostertag,Sara Mantero,Maria Teresa Conconi,Paolo Macchiarini +10 more
TL;DR: There was no development of anti-pig leukocyte antigen antibodies or increase in both IgM and IgG content in mice implanted with bioengineered tracheas and this method holds great promise for the future of tissue-engineered airway replacement.
Journal ArticleDOI
Early subclinical rejection as a risk factor for late chronic humoral rejection.
Francesc Moreso,Marta Carrera,Montse Gomà,Miguel Hueso,Joana Sellarés,Jaume Martorell,Josep M. Grinyó,Daniel Serón +7 more
TL;DR: Subclinical rejection in early protocol biopsies is associated with late appearance of chronic humoral rejection and interstitial fibrosis and tubular atrophy in renal transplants with a protocol biopsy performed within the first 6 months posttransplant between 1988 and 2006.
Journal ArticleDOI
Preformed circulating HLA-specific memory B cells predict high risk of humoral rejection in kidney transplantation
Marc Lúcia,Sergi Luque,Elena Crespo,Edoardo Melilli,Josep M. Cruzado,Jaume Martorell,Marta Jarque,Salvador Gil-Vernet,Anna Manonelles,Josep M. Grinyó,Oriol Bestard +10 more
TL;DR: Assessing donor-specific mBC frequencies may be relevant to better refine patient alloimmune-risk stratification, and provides new insight into the mechanisms of the adaptive humoral allo immune response taking place in kidney transplantation.