J
Javeed Ahmad Bhat
Researcher at Council of Scientific and Industrial Research
Publications - 17
Citations - 257
Javeed Ahmad Bhat is an academic researcher from Council of Scientific and Industrial Research. The author has contributed to research in topics: Medicine & Withania somnifera. The author has an hindex of 7, co-authored 10 publications receiving 159 citations. Previous affiliations of Javeed Ahmad Bhat include University of Rochester Medical Center.
Papers
More filters
Journal ArticleDOI
Creating superhydrophobic and antibacterial surfaces on gold by femtosecond laser pulses
Sohail A. Jalil,Sohail A. Jalil,Mahreen Akram,Javeed Ahmad Bhat,Jeffrey J. Hayes,Subhash C. Singh,Subhash C. Singh,Mohamed ElKabbash,Chunlei Guo,Chunlei Guo +9 more
TL;DR: It is shown that femtosecond laser processing turns originally hydrophilic Au to super-hydrophobic surface and the ability of the treated surface to reduce the adhesion of E. coli bacteria is demonstrated.
Journal ArticleDOI
Withanone, an Active Constituent from Withania somnifera, Affords Protection Against NMDA-Induced Excitotoxicity in Neuron-Like Cells
Nawab John Dar,Nawab John Dar,Javeed Ahmad Bhat,Naresh Kumar Satti,Parduman R. Sharma,Abid Hamid,Abid Hamid,Muzamil Ahmad,Muzamil Ahmad +8 more
TL;DR: Evaluating Withanone, one of the active constituents of Withania somnifera against NMDA-induced excitotoxicity in retinoic acid, differentiated Neuro2a cells suggests that Withan one may serve as potential neuroprotective agent.
Journal ArticleDOI
Understanding Histone Deacetylases in the Cancer Development and Treatment: An Epigenetic Perspective of Cancer Chemotherapy
Mudassier Ahmad,Abid Hamid,Aashiq Hussain,Rabiya Majeed,Yasrib Qurishi,Javeed Ahmad Bhat,Rauf Ahmad Najar,Asif Khurshid Qazi,Mohmmad Afzal Zargar,Shashank K. Singh,Ajit Kumar Saxena +10 more
TL;DR: It has been observed that cancer cells are more sensitive than nontransformed cells to apoptotic induction by some HDACi, andHDACi have emerged as important epigenetic target for single and combinatorial chemotherapy.
Journal ArticleDOI
Recent Development in Targeting PI3K-Akt-mTOR Signaling for Anticancer Therapeutic Strategies
Asif Khurshid Qazi,Aashiq Hussain,Abid Hamid,Yasrib Qurishi,Rabiya Majeed,Mudassier Ahmad,Rauf Ahmad Najar,Javeed Ahmad Bhat,Shashank K. Singh,Mohmmad Afzal Zargar,Shakir Ali,Ajit Kumar Saxena +11 more
TL;DR: The current review focuses on the structural features of various PI3K isoforms including Akt and mTOR and their inhibition using specific small molecule inhibitors in an attempt to achieve an attractive target for cancer prevention and chemotherapy.
Journal ArticleDOI
An anti-cancerous protein fraction from Withania somnifera induces ROS-dependent mitochondria-mediated apoptosis in human MDA-MB-231 breast cancer cells.
Parvaiz Ahmad Dar,Sameer Ahmad Mir,Javeed Ahmad Bhat,Abid Hamid,Laishram Rajendrakumar Singh,Fayaz Malik,Tanveer Ali Dar +6 more
TL;DR: WSPF exhibited apoptotic activity for each cancer cell line tested, demonstrating significant activity against MDA-MB-231 human breast cancer cells with an IC50 value of 92 μg/mL, indicating that the proteins in this fraction can be potential therapeutic agents for triple negative breast cancer treatment.