J
Javier Guerra
Researcher at University of Castilla–La Mancha
Publications - 34
Citations - 1017
Javier Guerra is an academic researcher from University of Castilla–La Mancha. The author has contributed to research in topics: Catalysis & Dendrimer. The author has an hindex of 17, co-authored 33 publications receiving 930 citations. Previous affiliations of Javier Guerra include University of Valladolid & University of Texas at Austin.
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Journal ArticleDOI
Barriers to Non-Viral Vector-Mediated Gene Delivery in the Nervous System
Francisco C. Pérez-Martínez,Javier Guerra,Inmaculada Posadas,Inmaculada Posadas,Valentín Ceña,Valentín Ceña +5 more
TL;DR: The barriers that different nanoparticles must overcome to efficiently deliver their cargo to central nervous system cells, including internalization into the neurons, interaction with intracellular organelles such as lysosomes, and transport across the nuclear membrane of the neuron in the case of DNA transfection are dealt with.
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NMR characterization of fourth-generation PAMAM dendrimers in the presence and absence of palladium dendrimer-encapsulated nanoparticles.
TL;DR: High-resolution solution NMR spectroscopy has been used to characterize the structure of Pd dendrimer-encapsulated nanoparticles (DENs) and shows that signals arising from the innermost methylenes of G4-OH(Pd(55)) are more highly influenced by the presence of the Pd nanoparticles than are the terminal functional groups.
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Hybrid materials based on Pd nanoparticles on carbon nanostructures for environmentally benign C–C coupling chemistry
TL;DR: This review highlights the latest advances in the synthetic design of these hybrid materials where carbon nanostructures act as supports as well as stabilizing agents for very reactive metallic nanoparticles in C-C coupling chemistry.
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Carbon nanohorns functionalized with polyamidoamine dendrimers as efficient biocarrier materials for gene therapy
Javier Guerra,M. Antonia Herrero,Blanca Carrión,Francisco C. Pérez-Martínez,Maribel Lucío,Noelia Rubio,Moreno Meneghetti,Maurizio Prato,Valentín Ceña,Ester Vázquez +9 more
TL;DR: The synthesis, structural characterization and biological data of new hybrid systems of carbon nanohorns that hold polyamidoamine dendrimers are reported, allowing for the conclusion that these nanomaterials can be exploited as useful non-viral agents for gene therapy.
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Gold dendrimer encapsulated nanoparticles as labeling agents for multiwalled carbon nanotubes.
M. Antonia Herrero,M. Antonia Herrero,Javier Guerra,V. Sue Myers,M. Victoria Gomez,Richard M. Crooks,Maurizio Prato +6 more
TL;DR: Electron microscopy and NMR spectroscopy confirm that the structures of the DENs and dendrimers are retained after immobilization on the surface of acid-functionalized MWNTs, suggesting that acid-induced debundling of the nanotubes is an essential prerequisite for attachment of nearly monodisperse DENs.