Jay R. Kostman

TL;DR: It is shown that HIV+ individuals have a significant decrease in the number of the Lin−HLA-DR+CD123+ and BDCA-2+ PDC compared with uninfected donors and that DC subsets are differentially reconstituted during the immune recovery associated with antiviral therapy.

TL;DR: A retrospective cohort study among antiretroviral-treated patients co-infected with HIV andHCV and HCV-monoinfected patients in the VACS-VC between 1 January 1997 and 30 September 2010 to suggest interventions to reduce the risk for end-stage liver disease in this population.

TL;DR: In the absence of antiretroviral therapy (ART), the results of several clinical trials support a predominantly antiviral activity (i.e., approximately 0.5 log decrease in plasma viral load) when interferon alfa is administered to HIV-1-infected persons.

TL;DR: Peg-interferon alfa-2a immunotherapy resulted in control of HIV replication and decreased HIV-1 integration, supporting a role for immunomediated approaches in HIV suppression and/or eradication.

TL;DR: The hypothesis that mature NK cell phenotype may be uncoupled from some mature functions following highly active antiretroviral therapy-mediated suppression of HIV-1 is supported, and relevant innate immune functions of NK cell subsets may remain altered despite effective viral suppression following antireTroviral treatment is indicated.