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Luis J. Montaner

Researcher at Wistar Institute

Publications -  215
Citations -  8701

Luis J. Montaner is an academic researcher from Wistar Institute. The author has contributed to research in topics: Immune system & Viral load. The author has an hindex of 48, co-authored 183 publications receiving 7522 citations. Previous affiliations of Luis J. Montaner include University of Oxford & University of Pennsylvania.

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Quantification of CD4, CCR5, and CXCR4 levels on lymphocyte subsets, dendritic cells, and differentially conditioned monocyte-derived macrophages.

TL;DR: It is found that macrophage colony-stimulating factor caused the greatest up-regulation of both CCR5 and CXCR4 on macrophages maturation, and Absolute ABS for CD4 and the major HIV-1 coreceptors serve as a more quantitative measure of cell surface expression.
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Cytokine storm and leukocyte changes in mild versus severe SARS-CoV-2 infection: Review of 3939 COVID-19 patients in China and emerging pathogenesis and therapy concepts.

TL;DR: Examining leukocyte and cytokine activity in COVID‐19 focuses on how these levels are altered as the disease progresses and proposed consequences to organ pathology and Viral and host interactions are described to gain further insight into leukocytes biology and how dysregulated cytokine responses lead to disease and/or organ damage.
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Constitutive and induced expression of DC-SIGN on dendritic cell and macrophage subpopulations in situ and in vitro.

TL;DR: The data demonstrate the relevant populations of DC andmacrophages that express DC‐SIGN in vivo where it may impact theefficiency of virus infection and indicate thatDC‐SIGN expression maybe involved in the Th2 axis of immunity.
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Persistent Decreases in Blood Plasmacytoid Dendritic Cell Number and Function Despite Effective Highly Active Antiretroviral Therapy and Increased Blood Myeloid Dendritic Cells in HIV-Infected Individuals

TL;DR: It is shown that HIV+ individuals have a significant decrease in the number of the Lin−HLA-DR+CD123+ and BDCA-2+ PDC compared with uninfected donors and that DC subsets are differentially reconstituted during the immune recovery associated with antiviral therapy.
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Interleukin-13 alters the activation state of murine macrophages in vitro: comparison with interleukin-4 and interferon-gamma.

TL;DR: IL‐13, like IL‐4, is a cytokine which has complex effects on Mϕ behavior, inducing activities characteristic of both activation and deactivation.