Jean-François Brichant

TL;DR: It is shown that default network connectivity is decreased in severely brain-damaged patients, in proportion to their degree of consciousness impairment, as well as in healthy controls and locked-in syndrome patients.

TL;DR: It is suggested that propofol-induced unconsciousness could be linked to a breakdown of cerebral temporal architecture that modifies both within- and between-network connectivity and thus prevents communication between low-level sensory and higher-order frontoparietal cortices, thought to be necessary for perception of external stimuli.

TL;DR: Two different pathophysiological mechanisms associated with preeclampsia are suggested, related to an overproduction of competitive soluble VEGFR-1 that may lead to suppression of VEGF-A and PlGF effects and the down-regulation of its membrane bound form in the placental bed, which may result in the defective uteroplacental development.

TL;DR: Propofol anesthesia is a sleep-like state and slow waves are associated with diminished consciousness even in the presence of high gamma activity.

TL;DR: Assessment of consciousness during anesthesia with propofol, xenon, and ketamine, independent of behavioral responsiveness, suggests that brain complexity may be sensitive to the presence of disconnected consciousness in subjects who are considered unconscious based on behavioral responses.