Jean-Jacques Body

TL;DR: Radioimmunoassay of calcitonin in normal human plasma is hindered by immunochemical heterogeneity in plasma, variable susceptibility of antisera to non-specific factors, limited assay sensitivity, and other problems.

TL;DR: In this article, drugs used for the prevention and the treatment of osteoporosis exert various favorable and unfavourable extra-skeletal effects whose importance is increasingly recognized notably for treatment selection.

TL;DR: Preliminary follow-up data on the pamidronate trial suggest prolongation of survival in the patients receiving second or subsequent lines of chemotherapy, and intravenous bisphosphonates can also exert clinically relevant analgesic effects in patients with metastatic bone pain.

TL;DR: It is shown that the net collagen amount produced in vitro by normal human osteoblasts and osteoblast-like cells was significantly reduced by culture medium conditioned by several BCC lines, including three newly isolated ones, suggesting that besides the eroding action of osteoclasts, BCC- and osteOBlast-derived MMPs and serine proteinases might play a direct role in bone collagen degradation in TIO.

TL;DR: This case report of giant cell granuloma involving the maxilla is of particular interest for two reasons: the locally aggressive clinical course contrasting with the diagnosis of a benign disease and the spectacular, although transient, response under steroid treatment.