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Jean-Jacques Body

Researcher at Université libre de Bruxelles

Publications -  397
Citations -  21506

Jean-Jacques Body is an academic researcher from Université libre de Bruxelles. The author has contributed to research in topics: Breast cancer & Zoledronic acid. The author has an hindex of 70, co-authored 384 publications receiving 19608 citations. Previous affiliations of Jean-Jacques Body include The Breast Cancer Research Foundation & University of California, San Francisco.

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A dose-finding study of zoledronate in hypercalcemic cancer patients.

TL;DR: An open‐label, dose‐finding, single‐dose phase I study in tumor‐induced hypercalcemia (TIH), which has been similarly used as a model to determine the active doses of other bisphosphonates, finding very low doses of zoledronate administered by a short‐time infusion effectively treated patients with TIH.
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Urinary pyridinium cross-links as markers of bone resorption in tumor-associated hypercalcemia

TL;DR: The urinary excretion of Pyr and D-Pyr was markedly increased in hypercalcemic cancer patients and was adequately lowered by bisphosphonate therapy, suggesting that these markers reflect different events of bone resorption.
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Evidence-based guidelines for the prevention and treatment of glucocorticoid-induced osteoporosis: a consensus document of the Belgian Bone Club.

TL;DR: There is indeed no proof that the increased costs of combined treatments will translate into increased therapeutic efficacy, but there is an increasing body of evidence supporting the antifracture efficacy of bisphosphonates, notably alendronate and risedronate.