Jean-Jacques Body

TL;DR: Aminobisphosphonates, especially zoledronic acid, markedly inhibited PC-3 cancer cell growth, through a variable combination of cytostatic and apoptotic effects.

TL;DR: The Belgian Bone Club aimed to provide a state of the art on the use of biochemical markers of bone turnover in different clinical or physiological situations like in postmenopausal women, osteoporosis in men, in elderly patients, in patients suffering from bone metastasis, in Patients with chronic renal failure, in pregnant or lactating women, in intensive care patients, and in diabetics.

TL;DR: Based on this and other dose‐response trials, this treatment can be safely and efficiently given as a single 24 h infusion or as daily 2 h infusions for 3 days and is recommend to give 1.0 to 1.5 mg of APD/kg body weight for the therapy of tumor‐associated hypercalcemia.

TL;DR: Data from four large international studies indicate that zoledronic acid is effective in the management of AIBL, and the results of ongoing studies should help define optimal bone health management for patients undergoing aromatase inhibitor treatment for early breast cancer.

TL;DR: The aim of rehabilitation is to promote global physical and psychosocial adjustment by acting at all modifiable levels, namely strengthening individual coping resources through psychotherapy, improving quantity and quality of familial and social support, and restoring optimal physical functioning.