Jean-Marc Léger

TL;DR: Revision of the guidelines on the use of skin biopsy in the diagnosis of peripheral neuropathy, published in 2005, has become appropriate owing to publication of more relevant articles and most of the new studies focused on small fiber neuropathy (SFN).

TL;DR: Ig is a promising therapeutic option for multifocal motor neuropathy with persistent conduction block and electrophysiological studies did not show significant differences at month 4 in motor parameters between IVIg patients and placebo patients.

TL;DR: The results confirm the frequency of autoimmune and infectious diseases associated with mixed cryoglobulinemias, whereas a lymphoproliferative syndrome was observed only in cases of cryoglOBulinemia with a monoclonal constituent or a microheterogeneity aspect, which was not always revealed by immunofixation or immunoelectrophoresis.

TL;DR: With the use of Cox-marginal structural models, rituximab plus corticosteroids showed the greater therapeutic efficacy, but this regimen was also associated with severe infections, particularly when high doses of cortICosteroids were used, whereas death rates did not differ between the therapeutic regimens.

TL;DR: In some of the patients in this study, LSS evolved into a more diffuse neuropathy sharing similarities with CIDP, while others had a clinical course characterized by a striking multifocal neuropathy, which suggests underlying mechanisms different from C IDP.