J
Jennifer L. Bento
Researcher at Wake Forest University
Publications - 10
Citations - 656
Jennifer L. Bento is an academic researcher from Wake Forest University. The author has contributed to research in topics: Single-nucleotide polymorphism & Type 2 diabetes. The author has an hindex of 10, co-authored 10 publications receiving 619 citations. Previous affiliations of Jennifer L. Bento include University of North Carolina at Charlotte.
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Journal ArticleDOI
Staphylococcus aureus Infection of Mouse or Human Osteoblasts Induces High Levels of Interleukin-6 and Interleukin-12 Production
Kenneth L. Bost,Warren K. Ramp,Natalie C. Nicholson,Jennifer L. Bento,Ian Marriott,Michael C. Hudson +5 more
TL;DR: These studies are the first to demonstrate induced IL-12p75 expression by osteoblasts and suggest a previously unrecognized role for osteoblast in initiating immune responses after S. aureus infection.
Journal ArticleDOI
Association of protein tyrosine phosphatase 1B gene polymorphisms with type 2 diabetes.
Jennifer L. Bento,Nicholette D. Palmer,Josyf C. Mychaleckyj,Leslie A. Lange,Carl D. Langefeld,Stephen S. Rich,Barry I. Freedman,Donald W. Bowden +7 more
TL;DR: A detailed association analysis of 23 noncoding SNPs spanning the 161-kb genomic region, which includes the PTPN1 gene, suggests that PTPn1 is a significant contributor to type 2 diabetes susceptibility in the Caucasian population.
Journal ArticleDOI
Association of protein tyrosine phosphatase 1B gene polymorphisms with measures of glucose homeostasis in Hispanic Americans: The Insulin Resistance atherosclerosis Study (IRAS) Family Study
Nicholette D. Palmer,Jennifer L. Bento,Josyf C. Mychaleckyj,Carl D. Langefeld,Joel K. Campbell,Jill M. Norris,Stephen M. Haffner,Richard N. Bergman,Donald W. Bowden +8 more
TL;DR: This comprehensive genetic analysis of PTPN1 reveals significant association with metabolic traits consistent with the proposed in vivo role for the PTP-1B protein.
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Induction of colony-stimulating factor expression following Staphylococcus or Salmonella interaction with mouse or human osteoblasts.
TL;DR: These studies are the first to define CSF expression and suggest that, following bacterial exposure, osteoblasts may influence osteoclastogenesis, as well as the development of an immune response, via the production of these cytokines.
Journal ArticleDOI
Monocyte chemoattractant protein-1 expression by osteoblasts following infection with Staphylococcus aureus or Salmonella.
Kenneth L. Bost,Jennifer L. Bento,Cynthia C. Petty,Laura W. Schrum,Michael C. Hudson,Ian Marriott +5 more
TL;DR: Two common pathogens of bone, Staphylococcus aureus and Salmonella, were investigated for their ability to induce chemokine expression in bone-forming osteoblasts to demonstrate a conserved osteoblast-derived MCP-1 response to two very different pathogens ofBone.