J
Jennifer L. McGuire
Researcher at University of Cincinnati
Publications - 39
Citations - 956
Jennifer L. McGuire is an academic researcher from University of Cincinnati. The author has contributed to research in topics: Traumatic brain injury & Fear conditioning. The author has an hindex of 16, co-authored 31 publications receiving 763 citations. Previous affiliations of Jennifer L. McGuire include University of Cincinnati Academic Health Center & Uniformed Services University of the Health Sciences.
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Journal ArticleDOI
Pavlovian fear memory circuits and phenotype models of PTSD
TL;DR: Pavlovian fear conditioning is a key tool for understanding both the neurobiology of fear and the mechanisms underlying variations in fear memory strength observed across different phenotypes in this article.
Journal ArticleDOI
Glutamate Neurotransmission in Rodent Models of Traumatic Brain Injury
Christopher R. Dorsett,Jennifer L. McGuire,Erica A K DePasquale,Amanda E. Gardner,Candace L. Floyd,Robert E. McCullumsmith +5 more
TL;DR: Dysregulation of extracellular glutamate and glutamate uptake in the acute stage of TBI and how failure to resolve acute disruptions in glutamate homeostatic mechanisms may play a causal role in chronic cognitive symptoms after TBI are discussed.
Journal ArticleDOI
Localization of mineralocorticoid receptors at mammalian synapses.
TL;DR: In this paper, the authors investigated the subcellular sites of mineralocorticoid receptors in the lateral amygdala of the Sprague-Dawley rat and found that they were expressed at both nuclear and extra nuclear sites including presynaptic terminals, neuronal dendrites, and dendritic spines.
Journal ArticleDOI
Enhanced fear recall and emotional arousal in rats recovering from chronic variable stress
TL;DR: Data are consistent with the constellation of symptoms associated with posttraumatic stress syndrome, such as re-experiencing, and arousal to fearful contexts, and the CVS-recovery paradigm may be useful to simulate trauma outcomes following chronic traumatization that is often associated with repeated combat stress.
Localization of Mineralocorticoid Receptors at Mammalian Synapses
Pedro Antonio Valdes-Sosa,Eric M. Prager,Jennifer Brielmaier,Hadley C. Bergstrom,Jennifer L. McGuire,Luke R. Johnson +5 more
TL;DR: Direct anatomical evidence is provided supporting the concept that, at some synapses, synaptic transmission is regulated by mineralocorticoid receptors, and part of the stress signaling response in the brain is a direct modulation of the synapse itself by adrenal steroids.