J
Jennifer R. Hiscock
Researcher at University of Kent
Publications - 84
Citations - 2699
Jennifer R. Hiscock is an academic researcher from University of Kent. The author has contributed to research in topics: Hydrogen bond & Chemistry. The author has an hindex of 22, co-authored 67 publications receiving 2315 citations. Previous affiliations of Jennifer R. Hiscock include University of Southampton.
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Journal ArticleDOI
Anion receptor chemistry: highlights from 2010
TL;DR: This critical review covers advances in anion complexation in the year 2010 and highlights the applications to which anion receptors can be applied such as sensing, anion transport, control of molecular motion and gelation.
Journal ArticleDOI
A synthetic ion transporter that disrupts autophagy and induces apoptosis by perturbing cellular chloride concentrations
Nathalie Busschaert,Seong Hyun Park,Kyung Hwa Baek,Yoon Pyo Choi,Jinhong Park,Ethan N. W. Howe,Jennifer R. Hiscock,Louise E. Karagiannidis,Igor Marques,Vítor Félix,Wan Namkung,Jonathan L. Sessler,Philip A. Gale,Injae Shin +13 more
TL;DR: It is shown that squaramide-based ion transporters enhance the transport of chloride anions in liposomal models and promote sodium chloride influx into the cytosol and is the first experimental evidence that synthetic ion transporter can disrupt both autophagy and induce apoptosis.
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1,3-Diindolylureas and 1,3-Diindolylthioureas: Anion Complexation Studies in Solution and the Solid State
TL;DR: These easy-to-make compounds adopt relatively planar conformations in the solid-state and are able to donate four hydrogen bonds and yet not fill the coordination sphere of carbonate or phosphate, allowing two or three receptors to bind to each anion in theSolid-state.
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1,3-Diindolylureas: high affinity dihydrogen phosphate receptors
Claudia Caltagirone,Philip A. Gale,Jennifer R. Hiscock,Simon J. Brooks,Michael B. Hursthouse,Mark E. Light +5 more
TL;DR: Neutral 1,3-di(1H-indol-7-yl)ureas are selective dihydrogen phosphate receptors in polar solvent mixtures (DMSO-d(6)-25% water).
Journal ArticleDOI
1,2,3-triazole-strapped calix[4]pyrrole: a new membrane transporter for chloride.
Matthew G. Fisher,Philip A. Gale,Jennifer R. Hiscock,Michael B. Hursthouse,Mark E. Light,Franz P. Schmidtchen,Christine C. Tong +6 more
TL;DR: A new triazole-strapped calix[4]pyrrole synthesised via'click' chemistry shows high affinity for chloride and lipid bilayer chloride transport properties.