Jennifer S. Herrick

TL;DR: It is concluded that the BRAF V600E mutation in microsatellite-stable colon cancer is associated with a significantly poorer survival in stages 2 to 4 colon cancer but has no effect on the excellent prognosis of micros satellite-unstable tumors.

TL;DR: The evaluation of a large, population-based sample of individuals with colon cancer strongly supports the biologic relevance of CIMP in colon cancer, however, the presence or absence of microsatellite instability has a major effect on the expression of this phenotype.

TL;DR: Previously identified associations between smoking and colon cancer, whether microsatellite unstable or stable, appear to be explained by the association of smoking with CIMP and BRAF mutations.

TL;DR: In conclusion, the conventional wisdom that most colon cancers contain APC, Ki-ras, and p53 mutations is incorrect and an analysis restricted to the MCR will miss more than half of APC mutations as well as mischaracterize their mutational spectrum.

TL;DR: In this paper, the associations of dietary patterns (western, prudent, Native Mexican, Mediterranean, and Dieter) with risk for breast cancer in Hispanic women (757 cases, 867 controls) and non-Hispanic white women (1524 cases, 1598 controls) from the Four-Corners Breast Cancer Study were examined.