Jenny Karlsson

TL;DR: In line with TERT expression being driven by active IRX2 regulatory elements, it is concluded that in addition to promoter mutations and epigenetic events, TERT can also be activated in tumors via formation of fusion transcripts.

TL;DR: In this article, the authors proposed a high-fidelity readout scheme for a single-instance approach to quantum computing in rare-earth ion-doped crystals, where the readout ions are doped into the material at a much lower concentration than the qubit ions.

TL;DR: In addition to cell death induction, antiangiogenic induction of differentiation may also be part of the in vivo effect of As2O3 on SCLC growth, as suggested by an increase in neuroendocrine markers in cultured cells.

TL;DR: It is suggested that clear cell sarcoma of the kidney arises from a mesodermal cell type that retains the capacity to initiate differentiation towards both nephrons and stroma, but remains locked in a primitive state.

TL;DR: Recovering the evolutionary histories of 56 pediatric primary tumors showed that the mutations most influencing relapse risk occur at initiation of clonal expansion in neuroblastoma and rhabdomyosarcoma, whereas in Wilms tumor, they are late events, suggesting some high-risk childhood cancers are born bad, whereas others grow worse over time.