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Jens F. Rehfeld

Researcher at University of Copenhagen

Publications -  682
Citations -  28636

Jens F. Rehfeld is an academic researcher from University of Copenhagen. The author has contributed to research in topics: Gastrin & Cholecystokinin. The author has an hindex of 82, co-authored 661 publications receiving 27079 citations. Previous affiliations of Jens F. Rehfeld include Panum Institute & University of Tartu.

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Distribution of peptide- and catecholamine-containing neurons in the gastro-intestinal tract of rat and guinea-pig: immunohistochemical studies with antisera to substance P, vasoactive intestinal polypeptide, enkephalins, somatostatin, gastrin/cholecystokinin, neurotensin and dopamine beta-hydroxylase.

TL;DR: The possible coexistence of two peptides in one neuron was studied and evidence was obtained for the occurrence of a somatostatin-like and a gastrin/ CCK-like peptide in the same neurons, which may indicate a common precursor for the two peptided in these particular neurons.
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Evidence for coexistence of dopamine and CCK in meso-limbic neurones.

TL;DR: Evidence has been obtained that mesencephalic dopamine neurones in the human brain contain similar peptides and the occurrence of peptides in meso-limbic dopamine neurons in the rat brain is described.
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Localization and molecular heterogeneity of cholecystokinin in the central and peripheral nervous system

TL;DR: Immunocytochemistry and radioimmunochemistry demonstrate the occurrence of the gastrointestinal hormone cholecystokinin (CCK) in both the central and peripheral nervous system of the guinea pig.
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Somatostatin cell processes as pathways for paracrine secretion

TL;DR: The findings suggest that somatostatin cells control the functions of other cells through local release of the peptide by way of cytoplasmic processes.
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Production and evaluation of antibodies for the radioimmunoassay of gastrin.

TL;DR: Only three antisera had antibodies with sufficient binding energy for radioimmunochemical determination of low physiologic concentrations of serum-gastrin (K0≥1011l/mol), and one of them reacted with cholecystokinin to an extent that made it unsuited for gastrin determinations in biologic fluids.