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Jessica Bowers

Researcher at Lawrence Livermore National Laboratory

Publications -  26
Citations -  1608

Jessica Bowers is an academic researcher from Lawrence Livermore National Laboratory. The author has contributed to research in topics: Nanocarriers & Chemistry. The author has an hindex of 9, co-authored 22 publications receiving 1514 citations.

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Optimized high-throughput microRNA expression profiling provides novel biomarker assessment of clinical prostate and breast cancer biopsies

TL;DR: Findings demonstrate that optimized high-throughput microRNA expression profiling offers novel biomarker identification from typically small clinical samples such as breast and prostate cancer biopsies.
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MicroRNAs as modulators of smoking-induced gene expression changes in human airway epithelium.

TL;DR: Examination of whole-genome miRNA and mRNA expression in bronchial airway epithelium from current and never smokers found 28 miRNAs to be differentially expressed (P < 0.05) with the majority being down-regulated in smokers.
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Genome-wide maps of circulating miRNA biomarkers for ulcerative colitis.

TL;DR: Analysis of whole genome maps of circulating miRNAs in micro-vesicles, Peripheral Blood Mononuclear Cells and platelets outlines a promising catalog of novel platelet-derived miRNA biomarkers of clinical utility and provides insight into the potential biological function of these candidates in disease pathogenesis.
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Rational probe optimization and enhanced detection strategy for microRNAs using microarrays.

TL;DR: Loyal A. Goff, Maocheng Yang, Jessica Bowers, Robert C. Getts, Richard W. Padgett and Ronald P. Hart are among the first recipients of the 2016 National Medal of Arts for services to the United States.
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Identification of methods for use of formalin-fixed, paraffin-embedded tissue samples in RNA expression profiling.

TL;DR: Using a random primer-based RNA amplification strategy, multiple protocols for the extraction and isolation of RNA from FFPE samples are evaluated and it is found that the RecoverAll RNA isolation procedure with three or four slices (ten-microns in thickness), supplemented with additional DNAse, gave optimal results.