J
Jessica Bowers
Researcher at Lawrence Livermore National Laboratory
Publications - 26
Citations - 1608
Jessica Bowers is an academic researcher from Lawrence Livermore National Laboratory. The author has contributed to research in topics: Nanocarriers & Chemistry. The author has an hindex of 9, co-authored 22 publications receiving 1514 citations.
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Journal ArticleDOI
Optimized high-throughput microRNA expression profiling provides novel biomarker assessment of clinical prostate and breast cancer biopsies
Michael D. Mattie,Christopher C. Benz,Jessica Bowers,Kelly Sensinger,Linda Wong,Gary K. Scott,Vita Fedele,David G. Ginzinger,Robert Getts,Christopher M. Haqq +9 more
TL;DR: Findings demonstrate that optimized high-throughput microRNA expression profiling offers novel biomarker identification from typically small clinical samples such as breast and prostate cancer biopsies.
Journal ArticleDOI
MicroRNAs as modulators of smoking-induced gene expression changes in human airway epithelium.
Frank Schembri,Sriram Sridhar,Catalina Perdomo,Adam M. Gustafson,Xiaoling Zhang,Ayla Ergun,Jining Lu,Gang Liu,Xiaohui Zhang,Jessica Bowers,Cyrus Vaziri,Kristen M. Ott,Kelly Sensinger,James J. Collins,Jerome S. Brody,Robert Getts,Marc E. Lenburg,Avrum Spira +17 more
TL;DR: Examination of whole-genome miRNA and mRNA expression in bronchial airway epithelium from current and never smokers found 28 miRNAs to be differentially expressed (P < 0.05) with the majority being down-regulated in smokers.
Journal ArticleDOI
Genome-wide maps of circulating miRNA biomarkers for ulcerative colitis.
Radha Duttagupta,Sharon DiRienzo,Rong Jiang,Jessica Bowers,Jeremy Gollub,Jessica Kao,Keith R. Kearney,David S. Rudolph,Noor Dawany,Michael K. Showe,Tom Stamato,Robert Getts,Keith W. Jones +12 more
TL;DR: Analysis of whole genome maps of circulating miRNAs in micro-vesicles, Peripheral Blood Mononuclear Cells and platelets outlines a promising catalog of novel platelet-derived miRNA biomarkers of clinical utility and provides insight into the potential biological function of these candidates in disease pathogenesis.
Journal ArticleDOI
Rational probe optimization and enhanced detection strategy for microRNAs using microarrays.
TL;DR: Loyal A. Goff, Maocheng Yang, Jessica Bowers, Robert C. Getts, Richard W. Padgett and Ronald P. Hart are among the first recipients of the 2016 National Medal of Arts for services to the United States.
Journal ArticleDOI
Identification of methods for use of formalin-fixed, paraffin-embedded tissue samples in RNA expression profiling.
Lisa R. Roberts,Jessica Bowers,Kelly Sensinger,Andrew Lisowski,Robert Getts,Mark G. Anderson +5 more
TL;DR: Using a random primer-based RNA amplification strategy, multiple protocols for the extraction and isolation of RNA from FFPE samples are evaluated and it is found that the RecoverAll RNA isolation procedure with three or four slices (ten-microns in thickness), supplemented with additional DNAse, gave optimal results.