J
Jeroen J. G. Geurts
Researcher at VU University Amsterdam
Publications - 212
Citations - 9995
Jeroen J. G. Geurts is an academic researcher from VU University Amsterdam. The author has contributed to research in topics: Multiple sclerosis & White matter. The author has an hindex of 54, co-authored 196 publications receiving 7889 citations. Previous affiliations of Jeroen J. G. Geurts include Centra & VU University Medical Center.
Papers
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Journal ArticleDOI
Intracortical Lesions in Multiple Sclerosis: Improved Detection with 3D Double Inversion-Recovery MR Imaging
Jeroen J. G. Geurts,Petra J. W. Pouwels,Bernard M. J. Uitdehaag,Chris H. Polman,Frederik Barkhof,Jonas A. Castelijns +5 more
TL;DR: In this paper, the depiction of intracortical lesions by using multislab three-dimensional (3D) double inversion-recovery (DIR), multiislab 3D fluid-attenuated inversion recovery (FLAIR), and T2-weighted spin-echo (SE) imaging in patients with multiple sclerosis was compared.
Journal ArticleDOI
Assessment of lesions on magnetic resonance imaging in multiple sclerosis: practical guidelines
Massimo Filippi,Paolo Preziosa,Brenda Banwell,Frederik Barkhof,Frederik Barkhof,Olga Ciccarelli,Olga Ciccarelli,Nicola De Stefano,Jeroen J. G. Geurts,Friedemann Paul,Daniel S. Reich,Ahmed T. Toosy,Anthony Traboulsee,Mike P. Wattjes,Tarek A. Yousry,Achim Gass,Catherine Lubetzki,Brian G. Weinshenker,Maria A. Rocca +18 more
TL;DR: A practical guide to the proper recognition of multiple sclerosis lesions is provided, including a thorough description and illustration of typical MRI features, as well as a discussion of red flags suggestive of alternative diagnoses.
Journal ArticleDOI
Cognitive impairment in multiple sclerosis: clinical management, MRI, and therapeutic avenues.
TL;DR: The Symbol Digit Modalities Test, or its computer-based analogues, can be used to monitor episodes of acute disease activity and data increasingly show that cognitive processing speed and memory are amenable to cognitive training interventions.
Journal ArticleDOI
Cortical atrophy patterns in multiple sclerosis are non-random and clinically relevant
Martijn D. Steenwijk,Jeroen J. G. Geurts,Marita Daams,Betty M. Tijms,Alle Meije Wink,Lisanne J. Balk,Prejaas Tewarie,Bernard M. J. Uitdehaag,Frederik Barkhof,Hugo Vrenken,Petra J. W. Pouwels +10 more
TL;DR: Cortical atrophy in multiple sclerosis occurs largely in a non-random manner and develops (at least partly) according to distinct anatomical patterns that showed stronger associations with clinical (especially cognitive) dysfunction than global cortical atrophy.
Journal ArticleDOI
Enhanced number and activity of mitochondria in multiple sclerosis lesions.
Maarten E. Witte,Lars Bø,Richard J. Rodenburg,Jeroen A.M. Beliën,René J. P. Musters,Thierry Hazes,Liesbeth T. Wintjes,Jan A.M. Smeitink,Jeroen J. G. Geurts,Helga E. de Vries,Paul van der Valk,Jack van Horssen +11 more
TL;DR: The data indicate the occurrence of severe mitochondrial alterations in multiple sclerosis lesions, which coincides with enhanced mitochondrial oxidative stress, which support a mechanism whereby enhanced density of mitochondria in MS lesions might contribute to the formation of free radicals and subsequent tissue damage.