J
Jessica J. Nadler
Researcher at University of North Carolina at Chapel Hill
Publications - 10
Citations - 3784
Jessica J. Nadler is an academic researcher from University of North Carolina at Chapel Hill. The author has contributed to research in topics: Autism & Social relation. The author has an hindex of 10, co-authored 10 publications receiving 3377 citations.
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Journal ArticleDOI
Sociability and preference for social novelty in five inbred strains: an approach to assess autistic-like behavior in mice
Sheryl S. Moy,Jessica J. Nadler,Antonio Perez,Ryan P. Barbaro,Josephine M. Johns,Terry Magnuson,Terry Magnuson,Joseph Piven,Jacqueline N. Crawley,Jacqueline N. Crawley +9 more
TL;DR: A new standardized procedure to quantitate sociability and preference for social novelty in mice provides a method to assess tendencies for social avoidance in mouse models of autism.
Journal ArticleDOI
Mouse behavioral tasks relevant to autism: Phenotypes of 10 inbred strains
Sheryl S. Moy,Jessica J. Nadler,Nancy B. Young,Antonio Perez,L. Paige Holloway,Ryan P. Barbaro,Justin R. Barbaro,Lindsay M. Wilson,David W. Threadgill,Jean M. Lauder,Terry Magnuson,Jacqueline N. Crawley,Jacqueline N. Crawley +12 more
TL;DR: A multitask strategy for modeling symptoms of autism will be useful for investigating targeted and random gene mutations, QTLs, and microarray analyses.
Journal ArticleDOI
Automated apparatus for quantitation of social approach behaviors in mice.
Jessica J. Nadler,Sheryl S. Moy,G. Dold,D. Trang,N. Simmons,Antonio Perez,Nancy B. Young,Ryan P. Barbaro,Joseph Piven,Terry Magnuson,Jacqueline N. Crawley,Jacqueline N. Crawley +11 more
TL;DR: An automated, three chambered apparatus designed to monitor social interaction in the mouse provides an accurate and objective approach to measuring social tendencies in mice and may allow higher‐throughput scoring of mouse social behaviors in mouse models of social dysfunction.
Journal ArticleDOI
Social approach in genetically engineered mouse lines relevant to autism.
Sheryl S. Moy,Jessica J. Nadler,Nancy B. Young,Randal J. Nonneman,A. W. Grossman,Dennis L. Murphy,A. J. D'Ercole,Jacqueline N. Crawley,Terry Magnuson,Jean M. Lauder +9 more
TL;DR: Overall, results show that loss of Fmr1 or Slc6a4 gene function can lead to deficits in sociability, and findings from the fragile X model suggest that the FVB/129 background confers enhanced susceptibility to consequences of FMR1 mutation on social approach.
Journal ArticleDOI
Social approach behaviors in oxytocin knockout mice: comparison of two independent lines tested in different laboratory environments.
Jacqueline N. Crawley,Thomas Chen,Amit Puri,Richard Washburn,Timothy L. Sullivan,Joanna M. Hill,Nancy B. Young,Jessica J. Nadler,Sheryl S. Moy,Larry J. Young,Heather K. Caldwell,W. Scott Young +11 more
TL;DR: Intact tendencies to spend time with another mouse versus with a novel object, in both lines of oxytocin knockouts, supports an interpretation that oxytoc in plays a highly specific role in social memory, but is not essential for general spontaneous social approach in mice.