J
Jacqueline N. Crawley
Researcher at University of California, Davis
Publications - 385
Citations - 48564
Jacqueline N. Crawley is an academic researcher from University of California, Davis. The author has contributed to research in topics: Galanin & Neuropeptide. The author has an hindex of 109, co-authored 384 publications receiving 45205 citations. Previous affiliations of Jacqueline N. Crawley include Pennsylvania State University & Nemours Foundation.
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Journal ArticleDOI
Atm-deficient mice: a paradigm of ataxia telangiectasia.
Carrolee Barlow,Shinji Hirotsune,Richard Paylor,Marek Liyanage,Michael Eckhaus,Francis J Collins,Yosef Shiloh,Jacqueline N. Crawley,Thomas Ried,Danilo A. Tagle,Anthony Wynshaw-Boris +10 more
TL;DR: Atm-disrupted mice recapitulate the ataxia telangiectasia phenotype in humans, providing a mammalian model in which to study the pathophysiology of this pleiotropic disorder.
Journal ArticleDOI
Behavioral phenotypes of inbred mouse strains: implications and recommendations for molecular studies.
Jacqueline N. Crawley,John K. Belknap,Allan C. Collins,John C. Crabbe,Wayne N. Frankel,Norman D. Henderson,Robert Hitzemann,Stephen C. Maxson,Lucinda L. Miner,Alcino J. Silva,Jeanne M. Wehner,Anthony Wynshaw-Boris,Richard Paylor +12 more
TL;DR: Strain distributions are described for open field activity, learning and memory tasks, aggression, sexual and parental behaviors, acoustic startle and prepulse inhibition, and the behavioral actions of ethanol, nicotine, cocaine, opiates, antipsychotics, and anxiolytics.
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Preliminary report of a simple animal behavior model for the anxiolytic effects of benzodiazepines
TL;DR: The increased exploratory activity with benzodiazepines does not appear to be a non-specific increase in general motor activity, as locomotion in clonazepam and chlordiazepoxide treated mice placed in a bare, undifferentiated cage was not significantly different from vehicle treated mice.
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Behavioural phenotyping assays for mouse models of autism
TL;DR: Robust phenotypes in mouse models hold great promise as translational tools for discovering effective treatments for components of autism spectrum disorders.
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Sociability and preference for social novelty in five inbred strains: an approach to assess autistic-like behavior in mice
Sheryl S. Moy,Jessica J. Nadler,Antonio Perez,Ryan P. Barbaro,Josephine M. Johns,Terry Magnuson,Terry Magnuson,Joseph Piven,Jacqueline N. Crawley,Jacqueline N. Crawley +9 more
TL;DR: A new standardized procedure to quantitate sociability and preference for social novelty in mice provides a method to assess tendencies for social avoidance in mouse models of autism.