J
Ji-Hun Jang
Researcher at Chonnam National University
Publications - 75
Citations - 460
Ji-Hun Jang is an academic researcher from Chonnam National University. The author has contributed to research in topics: Selected reaction monitoring & Triple quadrupole mass spectrometer. The author has an hindex of 8, co-authored 72 publications receiving 255 citations.
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Journal ArticleDOI
Anti-inflammatory effects of 6'-O-acetyl mangiferin from Iris rossii Baker via NF-κb signal blocking in lipopolysaccharide-stimulated RAW 264.7 cells.
Ji-Hun Jang,Kiho Lee,Ho-Kyung Jung,Mi-Ok Sim,Tae-Muk Kim,Kyeong-Wan Woo,Byeongkwan An,Jung-Hee Cho,Hyun-Woo Cho +8 more
TL;DR: The results suggest that the anti-inflammatory effects of OAM may be attributed to the downregulation of COX-2 and iNOS via the suppression of NF-κB and the MAPK signaling pathway in RAW264.7 macrophages.
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A sensitive UPLC–ESI–MS/MS method for the quantification of cinnamic acid in vivo and in vitro: application to pharmacokinetic and protein binding study in human plasma
TL;DR: The developed analytical method satisfied the criteria of international guidance and could be successfully applied to the pharmacokinetic study of cinnamic acid after oral administration of Socheongryong-tang tablets to humans.
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Gender differences in pharmacokinetics and tissue distribution of 4-n-nonylphenol in rats
TL;DR: There are gender differences in the PKs of 4-n-NP in rats, known to be a reproductive toxicant, and its excretion pattern, tissue distribution, and gender difference is expected to be very important for future risk assessment and PBPK model establishment.
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Oral delivery of topotecan in polymeric nanoparticles: Lymphatic distribution and pharmacokinetics.
TL;DR: In this article, a study was conducted on topotecan-loaded nanoparticles using poly(lactic-co-glycolic acid) (PLGA), which were prepared by double emulsion solvent evaporation.
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Simultaneous UPLC-MS/MS determination of four components of Socheongryong-tang tablet in human plasma: Application to pharmacokinetic study.
TL;DR: This analytical method developed satisfied the criteria of international guidance and could be successfully applied to pharmacokinetic studies of schizandrin, ephedrine, paeoniflorin, and cinnamic acid after oral administration of Socheongryong-tang tablet to humans.