J
Jiafu Wang
Researcher at Guizhou University
Publications - 26
Citations - 387
Jiafu Wang is an academic researcher from Guizhou University. The author has contributed to research in topics: Gene & Population. The author has an hindex of 10, co-authored 22 publications receiving 267 citations.
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Characterization and antitumor activity of camptothecin from endophytic fungus Fusarium solani isolated from Camptotheca acuminate.
TL;DR: The endophytic fungi from camptotheca trees are a reliable source for natural anticancer compounds and the fungal CPT exhibited effective activity at inhibiting cell growth and inducing apoptosis on Vero cells.
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Global copy number analyses by next generation sequencing provide insight into pig genome variation.
Jicai Jiang,Jiying Wang,Haifei Wang,Yan Zhang,Huimin Kang,Xiaotian Feng,Jiafu Wang,Zongjun Yin,Wenbin Bao,Qin Zhang,Jianfeng Liu +10 more
TL;DR: These studies lay out one way for characterization of CNVs in the pig genome, provide insight into the pork genome variation and prompt CNV mechanisms studies when using pigs as biomedical models for human diseases.
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Evidence of evolutionary history and selective sweeps in the genome of Meishan pig reveals its genetic and phenotypic characterization
Pengju Zhao,Ying Yu,Wen Feng,Heng Du,Jian Yu,Huimin Kang,Xianrui Zheng,Zhiquan Wang,George E. Liu,Catherine W Ernst,Xueqin Ran,Jiafu Wang,Jianfeng Liu +12 more
TL;DR: Findings will help explain the unique genetic and phenotypic characteristics of Meishan pigs and offer a plausible method for their utilization of Meischan pigs as valuable genetic resources in pig breeding and as an animal model for human wrinkled skin disease research.
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Structural Variant Detection by Large-scale Sequencing Reveals New Evolutionary Evidence on Breed Divergence between Chinese and European Pigs
Pengju Zhao,Junhui Li,Huimin Kang,Haifei Wang,Ziyao Fan,Zongjun Yin,Jiafu Wang,Qin Zhang,Zhiquan Wang,Jianfeng Liu +9 more
TL;DR: A genome-wide SV detection among the genomes of thirteen pigs from diverse Chinese and European originated breeds by next genetation sequencing, and a single-nucleotide resolution map involving 56,930 putative SVs is performed, it is found SVs can clearly detect the difference of genetic background among individuals.
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microRNA and mRNA Expression Profiling Analysis of Dichlorvos Cytotoxicity in Porcine Kidney Epithelial PK15 Cells
TL;DR: It is found that DIC inhibited the proliferation of PK15 cells in a dose- and time-dependent manner, which may result from apoptosis induced by DIC, which provides new insights into the role of miRNAs in the gene expression and function in DIC-related noncholinergic cytotoxicity.