J
Jiameng Zhang
Researcher at Genentech
Publications - 13
Citations - 1373
Jiameng Zhang is an academic researcher from Genentech. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 7, co-authored 9 publications receiving 1179 citations. Previous affiliations of Jiameng Zhang include Harvard University.
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Journal ArticleDOI
Rituximab in patients with primary progressive multiple sclerosis: Results of a randomized double-blind placebo-controlled multicenter trial†
Kathleen Hawker,Paul O'Connor,Mark S. Freedman,Peter A. Calabresi,Jack P. Antel,Jack H. Simon,Stephen L. Hauser,Emmanuelle Waubant,Timothy Vollmer,Hillel Panitch,Jiameng Zhang,Peter Chin,Craig H. Smith +12 more
TL;DR: Rituximab, a monoclonal antibody selectively depleting CD20+ B cells, has demonstrated efficacy in reducing disease activity in relapsing‐remitting multiple sclerosis (MS).
Journal ArticleDOI
Abnormal B-cell cytokine responses a trigger of T-cell-mediated disease in MS?
Amit Bar-Or,Lama Fawaz,Boli Fan,Peter J. Darlington,Aja Rieger,Christine Ghorayeb,Peter A. Calabresi,Emmanuelle Waubant,Stephen L. Hauser,Jiameng Zhang,Craig H. Smith +10 more
TL;DR: To study antibody‐independent contributions of B cells to inflammatory disease activity, and the immune consequences of B‐cell depletion with rituximab, in patients with multiple sclerosis (MS).
Journal ArticleDOI
A simple local sensitivity analysis tool for nonignorable coarsening: application to dependent censoring.
Jiameng Zhang,Daniel F. Heitjan +1 more
TL;DR: A simple sensitivity analysis tool is extended, the index of local sensitivity to nonignorability of the coarsening process in the general coarse-data model is converted into a simple graphical display, and the validity of the method is illustrated.
Journal ArticleDOI
Impact of nonignorable coarsening on Bayesian inference.
Jiameng Zhang,Daniel F. Heitjan +1 more
TL;DR: This paper derives formulas for a range of models and applies the method to evaluate sensitivity to nonignorability in 2 real data examples, one involving missing CD4 counts in an HIV trial and the other involving potentially informatively censored relapse times in a leukemia trial.
Journal ArticleDOI
Nonignorable censoring in randomized clinical trials
Jiameng Zhang,Daniel F. Heitjan +1 more
TL;DR: A graphical method for analyzing sensitivity of estimates of survival model parameters to small departures from nonignorable censoring is demonstrated and applied to a clinical trial evaluating the survival benefit of a surgically implanted left ventricular assist device in subjects with end-stage heart failure.