J
Jiang Qian
Researcher at Albany Medical College
Publications - 5
Citations - 271
Jiang Qian is an academic researcher from Albany Medical College. The author has contributed to research in topics: Meningioma & Epileptogenesis. The author has an hindex of 3, co-authored 5 publications receiving 218 citations.
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Journal ArticleDOI
Impaired Autophagy in Neurons after Disinhibition of Mammalian Target of Rapamycin and Its Contribution to Epileptogenesis
John J. McMahon,Xiaoxing Huang,Jun Yang,Masaaki Komatsu,Zhenyu Yue,Jiang Qian,Xinjun Zhu,Yunfei Huang +7 more
TL;DR: Autophagy is suppressed in brain tissues of forebrain-specific conditional TSC1 and phosphatase and tensin homlog knock-out mice and impaired autophagy contributes to epileptogenesis, which may be of interest as a potential therapeutic target for epilepsy treatment and/or prevention.
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Noninflammatory Changes of Microglia Are Sufficient to Cause Epilepsy.
Xiao-Feng Zhao,Yuan Liao,Shannon Morgan,Ramkumar Mathur,Paul J. Feustel,Joseph E. Mazurkiewicz,Jiang Qian,Julia W. Chang,Gary W. Mathern,Matthew A. Adamo,Anthony L. Ritaccio,Michael Gruenthal,Xinjun Zhu,Yunfei Huang +13 more
TL;DR: It is demonstrated that elevated mTOR signaling in mouse microglia leads to phenotypic changes, including an amoeboid-like morphology, increased proliferation, and robust phagocytosis activity, but without a significant induction of pro-inflammatory cytokines.
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A carcinoid tumor mimicking an isolated intracranial meningioma: Case report
TL;DR: The authors concluded that this intracranial carcinoid tumor was the primary lesion despite its unusual location and that it should be included in the differential diagnosis of dural-based, extraaxial brain lesions.
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A familial syndrome of hypothalamic hamartomas, polydactyly, and SMO mutations: a clinical report of 2 cases.
TL;DR: This is the first report in the literature describing a familial syndrome caused by germline mutations in the Smoothened (SMO) gene and the first familial syndrome associated with hypothalamic hamartomas other than Pallister-Hall syndrome.
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Giant Intracranial Extraaxial Parietal-Occipital Cavernous Hemangioma in an Adolescent.
TL;DR: C cavernous hemangiomas should be considered in the differential diagnosis of pediatric extra-axial masses and pre-operative hemorrhage control efforts should be pursued to reduce adverse outcomes stemming from resection of vascular malformations such as EACHs.