M
Michael Gruenthal
Researcher at Albany Medical College
Publications - 9
Citations - 387
Michael Gruenthal is an academic researcher from Albany Medical College. The author has contributed to research in topics: Epilepsy & Epileptogenesis. The author has an hindex of 5, co-authored 9 publications receiving 340 citations.
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Journal ArticleDOI
Pharmacological inhibition of the mammalian target of rapamycin pathway suppresses acquired epilepsy
Xiaoxing Huang,Hailong Zhang,Jun Yang,Jingfan Wu,John J. McMahon,Yufan Lin,Zhonglian Cao,Michael Gruenthal,Yunfei Huang +8 more
TL;DR: The mTOR pathway was examined in rats that had already developed chronic spontaneous seizures in a pilocarpine model and it was found that mTOR is aberrantly activated in brain tissues from rats with chronic seizures.
Journal ArticleDOI
Noninflammatory Changes of Microglia Are Sufficient to Cause Epilepsy.
Xiao-Feng Zhao,Yuan Liao,Shannon Morgan,Ramkumar Mathur,Paul J. Feustel,Joseph E. Mazurkiewicz,Jiang Qian,Julia W. Chang,Gary W. Mathern,Matthew A. Adamo,Anthony L. Ritaccio,Michael Gruenthal,Xinjun Zhu,Yunfei Huang +13 more
TL;DR: It is demonstrated that elevated mTOR signaling in mouse microglia leads to phenotypic changes, including an amoeboid-like morphology, increased proliferation, and robust phagocytosis activity, but without a significant induction of pro-inflammatory cytokines.
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Infant botulism: two recent cases and literature review.
TL;DR: A comprehensive review of the literature regarding infant botulism in the United States is presented, wherein the pathophysiology, clinical features, epidemiology, and treatment are discussed.
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Core elements of epilepsy diagnosis and management: expert consensus from the Leadership in Epilepsy, Advocacy, and Development (LEAD) faculty.
Tracy A. Glauser,Raman Sankar,Jacquelyn L. Bainbridge,Martina Bebin,Selim R. Benbadis,Deborah T.C. Cantrell,R. Edward Faught,Michael Gruenthal,Laura L. Hershkowitz,Gregory L. Holmes,Aatif M. Husain,David M. Labiner,Georgia Montouris,Dean K. Naritoku,Barbara J. Olson,John M. Pellock,Patricia Penovich,Michael Privitera,R. Eugene Ramsay,Jong M. Rho,Karen C. Richards,William E. Rosenfeld,Jeremy D. Slater,Michael C. Smith,Mark C. Spitz,John M. Stern,David G. Vossler,James W. Wheless +27 more
TL;DR: The core elements of epilepsy management identified here suggest minimum standards that can be used across all settings to improve consistency and quality of epilepsy diagnosis and care.
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The national temporal lobectomy survey
TL;DR: The data show that the neurological community currently does not have consistent definitions and practices in the management of pharmacoresistant epilepsy, and there appears to be need for developing a unified approach.