J
Jianzhong Shi
Researcher at Harbin Veterinary Research Institute
Publications - 87
Citations - 5871
Jianzhong Shi is an academic researcher from Harbin Veterinary Research Institute. The author has contributed to research in topics: Influenza A virus subtype H5N1 & Virus. The author has an hindex of 28, co-authored 77 publications receiving 4541 citations.
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Susceptibility of ferrets, cats, dogs, and other domesticated animals to SARS-coronavirus 2.
Jianzhong Shi,Zhiyuan Wen,Gongxun Zhong,Huanliang Yang,Chong Wang,Baoying Huang,Renqiang Liu,Xijun He,Lei Shuai,Ziruo Sun,Yubo Zhao,Peipei Liu,Libin Liang,Pengfei Cui,Jinliang Wang,Xianfeng Zhang,Yuntao Guan,Wenjie Tan,Guizhen Wu,Hualan Chen,Zhigao Bu +20 more
TL;DR: It is found that SARS-CoV-2 replicates poorly in dogs, pigs, chickens, and ducks, but ferrets and cats are permissive to infection and Additionally, cats are susceptible to airborne transmission.
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Properties and dissemination of H5N1 viruses isolated during an influenza outbreak in migratory waterfowl in western China
Hualan Chen,Yanbing Li,Zejun Li,Jianzhong Shi,Kyoko Shinya,Kyoko Shinya,Guohua Deng,Qiaoling Qi,Guobin Tian,Shufang Fan,Haidan Zhao,Yingxiang Sun,Yoshihiro Kawaoka,Yoshihiro Kawaoka +13 more
TL;DR: H5N1 viruses isolated in Mongolia, Russia, Inner Mongolia, and the Liaoning Province of China after August 2005 were genetically closely related to one of the genotypes isolated during the Qinghai outbreak, suggesting the dominant nature of this genotype and underscoring the need for worldwide intensive surveillance to minimize its devastating consequences.
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H7N9 Influenza Viruses Are Transmissible in Ferrets by Respiratory Droplet
Qianyi Zhang,Qianyi Zhang,Jianzhong Shi,Guohua Deng,Jing Guo,Xianying Zeng,Xijun He,Huihui Kong,Chunyang Gu,Chunyang Gu,Xuyong Li,Jinxiong Liu,Guojun Wang,Guojun Wang,Yan Chen,Liling Liu,Libin Liang,Yuanyuan Li,Jun Fan,Jinliang Wang,Wenhui Li,Lizheng Guan,Qimeng Li,Qimeng Li,Huanliang Yang,Pucheng Chen,Li Jiang,Yuntao Guan,Xiaoguang Xin,Yongping Jiang,Guobin Tian,Xiurong Wang,Chuanling Qiao,Chengjun Li,Zhigao Bu,Hualan Chen,Hualan Chen +36 more
TL;DR: A large survey of H7N9 influenza viruses in China reveals a spectrum of mutation and virulence, with one virus isolated from humans was highly transmissible in ferrets by respiratory droplet and another caused up to 30% body weight loss in mice.
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Identification of amino acids in HA and PB2 critical for the transmission of H5N1 avian influenza viruses in a mammalian host.
Yuwei Gao,Ying Zhang,Kyoko Shinya,Guohua Deng,Yongping Jiang,Zejun Li,Yuntao Guan,Guobin Tian,Yanbing Li,Jianzhong Shi,Liling Liu,Xianying Zeng,Zhigao Bu,Xianzhu Xia,Yoshihiro Kawaoka,Yoshihiro Kawaoka,Yoshihiro Kawaoka,Hualan Chen +17 more
TL;DR: The authors' mutagenesis analysis revealed that the amino acid asparagine at position 701 in the PB2 protein was a prerequisite for DKGX/35 transmission in guinea pigs, and an amino acid change in the hemagglutinin (HA) protein was responsible for HA binding to sialylated glycans and was critical for H5N1 virus transmission in Guinea pigs.
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Newcastle Disease Virus-Based Live Attenuated Vaccine Completely Protects Chickens and Mice from Lethal Challenge of Homologous and Heterologous H5N1 Avian Influenza Viruses
Jinying Ge,Guohua Deng,Zhiyuan Wen,Guobing Tian,Yong Wang,Jianzhong Shi,Xijun Wang,Yanbing Li,Sen Hu,Yongping Jiang,Chinglai Yang,Kangzhen Yu,Zhigao Bu,Hualan Chen +13 more
TL;DR: The results indicate that recombinant NDV is suitable as a bivalent live attenuated vaccine against both NDV and AIV infection in poultry and may also have potential use in high-risk human individuals to control the pandemic spread of lethal avian influenza.