J
Jieru Han
Researcher at Heilongjiang University of Chinese Medicine
Publications - 8
Citations - 109
Jieru Han is an academic researcher from Heilongjiang University of Chinese Medicine. The author has contributed to research in topics: Cardiac function curve & Heart failure. The author has an hindex of 3, co-authored 7 publications receiving 32 citations.
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Journal ArticleDOI
Exploration of the mechanism of Zisheng Shenqi decoction against gout arthritis using network pharmacology
TL;DR: The PPI network, GO enrichment analysis and KEGG pathway enrichment analysis suggested that ZSD can exerte anti-inflammatory and analgesic effects on the treatment of GA by reducing decreasing inflammatory reaction, alleviating ROS accumulation, and attenuating pain.
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Zisheng Shenqi decoction ameliorates monosodium urate crystal-induced gouty arthritis in rats through anti-inflammatory and anti-oxidative effects
Jieru Han,Ying Xie,Fangyu Sui,Chunhong Liu,Xiao-Wei Du,Cheng-Gang Liu,Xiaoling Feng,Deyou Jiang +7 more
TL;DR: Results indicated that ZSD effectively prevented MSU crystal-induced gouty arthritis via modulating multiple anti-oxidative and anti-inflammatory pathways, suggesting a promising herbal formula for the prevention and treatment of goutY arthritis.
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Preventive effect of dioscin against monosodium urate-mediated gouty arthritis through inhibiting inflammasome NLRP3 and TLR4/NF-κB signaling pathway activation: an in vivo and in vitro study
TL;DR: Dioscin had a protective effect against MSU-initiated inflammatory response via repressing the production of inflammatory cytokines and the activation of inflammasome NLRP3 and TLR4/NF-κB signaling pathway.
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Qiliqiangxin improves cardiac function and attenuates cardiac remodelling in doxorubicin-induced heart failure rats.
TL;DR: The beneficial effects of QL on DOX-induced CHF in rats are mediated by reduction in myocardial fibrosis, promotion of TGF-β3/Smad7, and inhibition of T GF-β1/ Smad3, which may also modulate specific miRNAs.
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Atractylenolide III Improves Mitochondrial Function and Protects Against Ulcerative Colitis by Activating AMPK/SIRT1/PGC-1α
TL;DR: Findings support that AT III may protect against mitochondrial dysfunction by the activation of the AMPK/SIRT1/PGC-1α signaling pathway during UC development.