Jim Gray

TL;DR: Care must be taken to choose an assay with high specificity in order to accurately assess the need for vaccination or immunoprophylaxis; however, high sensitivity is preferable to prevent inappropriate and expensive treatment.

TL;DR: A time resolved fluorescence immunoassay (TRFIA) for VzV IgG using British Standard VZV antibody has been developed and standardised and the limit of detection by this assay was of the order 39-78mIU/ml.

TL;DR: The evidence suggests that transmission between hospitals units does occur and the combined molecular/epidemiologic approach presented here could be applied to other viral populations and potentially to other pathogens for a more thorough view of transmission.

TL;DR: The use of reverse transcription–polymerase chain reaction (RT–PCR) to identify asymptomatic enteric infections in a birth cohort followed for rotaviral infections in an south Indian urban slum is reported.

TL;DR: The clinical symptoms associated with rotavirus (RV) gastroenteritis are not sufficiently characteristic to distinguish between RV infection and other causes as mentioned in this paper, therefore, laboratory procedures, including electron microscopy (EM), enzyme-linked immunosorbent assays (ELISA), passive particle agglutination tests (PPAT), or reverse transcription-polymerase chain reaction (RT-PCR) are necessary to confirm a clinical diagnosis of RV gastroenter infections.