J
Jin-Song Bian
Researcher at National University of Singapore
Publications - 141
Citations - 9130
Jin-Song Bian is an academic researcher from National University of Singapore. The author has contributed to research in topics: Oxidative stress & Protein kinase C. The author has an hindex of 50, co-authored 132 publications receiving 7355 citations. Previous affiliations of Jin-Song Bian include Southern University of Science and Technology & Albert Einstein College of Medicine.
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Journal ArticleDOI
Neuroprotective effects of hydrogen sulfide on Parkinson’s disease rat models
TL;DR: It is demonstrated for the first time that H2S may serve as a neuroprotectant to treat and prevent neurotoxin‐induced neurodegeneration via multiple mechanisms including anti‐oxidative stress, anti‐inflammation and metabolic inhibition and therefore has potential therapeutic value for treatment of PD.
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Hydrogen sulfide attenuates lipopolysaccharide‐induced inflammation by inhibition of p38 mitogen‐activated protein kinase in microglia
TL;DR: H2S produced an anti‐inflammatory effect in LPS‐stimulated microglia and astrocytes, which may be due to inhibition of inducible nitric oxide synthase and p38 MAPK signaling pathways.
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Antioxidant response elements: Discovery, classes, regulation and potential applications.
Azhwar Raghunath,Kiruthika Sundarraj,R. Nagarajan,Frank Arfuso,Jin-Song Bian,Alan Prem Kumar,Gautam Sethi,Ekambaram Perumal +7 more
TL;DR: A thorough understanding of AREs will pave the way for the development of therapeutic agents against cancer, neurodegenerative, cardiovascular, metabolic and other diseases with oxidative stress.
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Role of Hydrogen Sulfide in the Cardioprotection Caused by Ischemic Preconditioning in the Rat Heart and Cardiac Myocytes
Jin-Song Bian,Qian Chen Yong,Ting-Ting Pan,Zhan-Ning Feng,Muhammed Yusuf Ali,Shu-Feng Zhou,Philip K. Moore +6 more
TL;DR: It is suggested that endogenous H2S contributes to cardioprotection induced by IP, which effect may involve protein kinase C and sarcolemmal KATP channels.
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A Review of Hydrogen Sulfide Synthesis, Metabolism, and Measurement: Is Modulation of Hydrogen Sulfide a Novel Therapeutic for Cancer?
Xu Cao,Lei Ding,Zhi-Zhong Xie,Yong Yang,Yong Yang,Matthew Whiteman,Philip K. Moore,Jin-Song Bian +7 more
TL;DR: A bell-shaped model has been proposed to explain the role of H2S in cancer development and indicates that inhibition of H1N1 biosynthesis and H1S supplementation serve as two distinct ways for cancer treatment.