Jin-Ye Wang

TL;DR: It is demonstrated that zein is a promising biomaterial with good biocompatibility for the development of tissue engineering and attachment, extensibility and proliferation of cells on them.

TL;DR: Rat mesebchymal stem cells (MSCs) could adhere, grow, proliferate and differentiate toward osteoblasts on porous zein scaffold and showed a relative higher activity of alkaline phosphatase (ALP) and a higher proliferating activity (p<0.05) than those of MSCs without dexamethasone.

TL;DR: A successful improvement of mechanical properties, especially the brittleness of the zein scaffold could be achieved, and a good tissue response and degradability was revealed.

TL;DR: The results showed that the complexes of zein scaffolds and rabbit MSCs could undergo ectopic bone formation in the thigh muscle pouches of nude mice and could lead to the repair of critical-sized radius defects in rabbits accompanied with blood vessels' formation, which clearly demonstrates promise for the treatment of bone defects through tissue engineering.

TL;DR: Zein conduit with microtubes yielded satisfactory results in sciatic function index, proximal compound muscle action potentials, density of myelinated nerve fibres and myelin thickness, which were not inferior to autograft but slightly superior to the hollow conduit at the 4th month post-implantation.