J
Jin Zhou
Researcher at Tianjin University of Science and Technology
Publications - 7
Citations - 212
Jin Zhou is an academic researcher from Tianjin University of Science and Technology. The author has contributed to research in topics: Autophagy & HeLa. The author has an hindex of 5, co-authored 7 publications receiving 59 citations.
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CRISPR-Cas13a based bacterial detection platform: Sensing pathogen Staphylococcus aureus in food samples.
TL;DR: CCB-Detection was successfully applied for sensing S. aureus in real food samples with both known and unknown amounts bacteria and its performance is comparable to the conventional culture-based counting method but with short assay time and high sensitivity.
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CRISPR-Cas12a based aptasensor for sensitive and selective ATP detection
TL;DR: The target DNA-induced non-specific single-stranded DNA cutting activity of CRISPR-Cas12a is utilised to fabricate an aptamer mediated fluorescent biosensor for sensitive and selective detection of adenosine triphosphate (ATP).
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Integration of logic gates to CRISPR/Cas12a system for rapid and sensitive detection of pathogenic bacterial genes.
TL;DR: The results not only validated the possibility of using CRISPR-Cas systems for constructing bio-computing devices but also provided a prototype of biosensor for rapid and intelligent pathogenic bacteria detection.
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A cardiac glycoside HTF-1 isolated from Helleborus thibetanus Franch displays potent in vitro anti-cancer activity via caspase-9, MAPK and PI3K-Akt-mTOR pathways.
Long Ma,Yuanyuan Meng,Chunhao Tu,Xiuqi Cao,Haiyue Wang,Yuyin Li,Shuli Man,Jin Zhou,Miao Li,Zhenxing Liu,Yanfang Su +10 more
TL;DR: This work has found that HTF-1 induces apoptosis against several types of cancer cells in a concentration- and time-dependent manner, and will enrich the understanding of CGs and pave the way for natural product-based anti-cancer drug development.
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Polyethyleneimine coated Fe3O4 magnetic nanoparticles induce autophagy, NF-κB and TGF-β signaling pathway activation in HeLa cervical carcinoma cells via reactive oxygen species generation.
TL;DR: It is found that autophagy induction and NF-κB and TGF-β activation can be efficiently suppressed through the inhibition of PEI-MNP dependent reactive oxygen species (ROS) over-production, and would be useful for designing MNPs induced ROS anti-cancer strategies or diminishing long-term toxic effects.