J
Jing Liang
Researcher at Yunnan University
Publications - 3
Citations - 831
Jing Liang is an academic researcher from Yunnan University. The author has contributed to research in topics: Protein ligand & Docking (molecular). The author has an hindex of 3, co-authored 3 publications receiving 497 citations.
Papers
More filters
Journal ArticleDOI
Insights into Protein-Ligand Interactions: Mechanisms, Models, and Methods
Xing Du,Yi Li,Yuan-Ling Xia,Shi-Meng Ai,Shi-Meng Ai,Jing Liang,Peng Sang,Peng Sang,Xing-Lai Ji,Shu-Qun Liu +9 more
TL;DR: The physicochemical mechanisms underlying protein–ligand binding, including the binding kinetics, thermodynamic concepts and relationships, and binding driving forces, are introduced and rationalized.
Journal ArticleDOI
Comparative thermal unfolding study of psychrophilic and mesophilic subtilisin-like serine proteases by molecular dynamics simulations
Xing Du,Peng Sang,Yuan Ling Xia,Yi Li,Jing Liang,Shi Meng Ai,Xing Lai Ji,Yunxin Fu,Shu Qun Liu +8 more
TL;DR: Insight is provided into molecular basis of thermostability of homologous serine proteases adapted to different temperatures and the increased flexibility of VPR would be most likely caused by its reduced intramolecular interactions and more favourable protein-solvent interactions arising from the larger exposure of the polar area.
Journal ArticleDOI
Molecular dynamics simulations reveal distinct differences in conformational dynamics and thermodynamics between the unliganded and CD4-bound states of HIV-1 gp120
TL;DR: Microsecond-scale multiple-replica molecular dynamics simulations are performed to explore the differences in the conformational dynamics, protein motions, and thermodynamics between the unliganded and CD4-bound/complexed forms of gp120 to better understand the functional and immunological properties of the virus.