J
Jing Wang
Researcher at Peking Union Medical College Hospital
Publications - 16
Citations - 232
Jing Wang is an academic researcher from Peking Union Medical College Hospital. The author has contributed to research in topics: Medicine & Microsatellite instability. The author has an hindex of 4, co-authored 11 publications receiving 81 citations.
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Journal ArticleDOI
Whole-genome sequencing reveals distinct genetic bases for insulinomas and non-functional pancreatic neuroendocrine tumours: leading to a new classification system
Xiafei Hong,Sitan Qiao,Fuqiang Li,Wenze Wang,Rui Jiang,Huanwen Wu,Chen Hao,Liu Lulu,Peng Junya,Jing Wang,Congwei Jia,Xiaolong Liang,Hongmei Dai,Jialin Jiang,Taiping Zhang,Quan Liao,Menghua Dai,Lin Cong,Xianlin Han,Dan Guo,Zhi-Yong Liang,Li Dongjing,Zetian Zheng,Chen Ye,Siliang Li,Yupei Zhao,Kui Wu,Wenming Wu +27 more
TL;DR: Whole-genome/whole-exome sequencing data allowed a comprehensive assessment of genetic differences between insulinomas and NF-PanNETs, reclassifying these tumours into novel molecular subtypes and proposed a novel relapse risk stratification system using CNV patterns and DAXX/ATRX mutations.
Journal ArticleDOI
Prevalence of recurrent oncogenic fusion in mismatch repair-deficient colorectal carcinoma with hypermethylated MLH1 and wild-type BRAF and KRAS
Jing Wang,Yuting Yi,Yi Xiao,Lin Dong,Li Liang,Lianghong Teng,Jian Ming Ying,Tao Lu,Yuanyuan Liu,Yanfang Guan,Junyi Pang,Lianrui Zhou,Junliang Lu,Zhiwen Zhang,Xiaoding Liu,Xiaolong Liang,Xuan Zeng,Xin Yi,Weixun Zhou,Xuefeng Xia,Ling Yang,Jianjun Zhang,Scott Kopetz,P. Andrew Futreal,Huanwen Wu,Zhiyong Liang +25 more
TL;DR: Oncogenic fusions were highly enriched and frequently detected in mismatch repair-deficient colorectal carcinomas with MLH1 hypermethylation and wild-type BRAF and KRAS, and were associated with poor prognosis and high tumor CD274(PD-L1) expression.
Journal ArticleDOI
Mismatch Repair Deficiency and Microsatellite Instability in Triple-Negative Breast Cancer: A Retrospective Study of 440 Patients
Xinyu Ren,Yu Song,Jing Wang,Long-Yun Chen,Junyi Pang,Liangrui Zhou,Songjie Shen,Xi Cao,Yu-Xin Wang,Miao-Miao Shao,Zhiyong Liang,Qiang Sun,Huanwen Wu +12 more
TL;DR: In this article, the status of mismatch repair (MMR) and microsatellite instability (MSI) in triple-negative breast cancer (TNBC) was investigated and correlations between MMR/MSI status and clinicopathological parameters and prognosis were analyzed.
Journal ArticleDOI
Germline and Somatic BRCA1/2 Mutations in 172 Chinese Women With Epithelial Ovarian Cancer.
TL;DR: In Chinese EOC patients, the distributions and risk factors associated with germline and somatic BRCA1/2 mutations were similar to those previously reported in international studies.
Journal ArticleDOI
Triple-Negative Breast Cancer: Intact Mismatch Repair and Partial Co-Expression of PD-L1 and LAG-3.
TL;DR: In this paper, the status of mismatch repair (MMR), microsatellite instability (MSI), programmed death-ligand 1 (PD-L1), and lymphocyte activation gene 3 (LAG-3) in triple negative breast cancer (TNBC) cases was investigated.