J
Jing Zhang
Researcher at Zhejiang University
Publications - 5
Citations - 161
Jing Zhang is an academic researcher from Zhejiang University. The author has contributed to research in topics: Epithelial–mesenchymal transition & Cancer. The author has an hindex of 3, co-authored 5 publications receiving 108 citations. Previous affiliations of Jing Zhang include Hebei Medical University.
Papers
More filters
Journal ArticleDOI
IL-13/STAT6 signaling plays a critical role in the epithelial-mesenchymal transition of colorectal cancer cells
TL;DR: It is shown that the pleiotropic cytokine interleukin-13 (IL-13) could induce an aggressive phenotype displaying EMT by enhancing the expression of EMT-promoting factor ZEB1 and the STAT6 signaling inhibitor and STAT6 knockdown significantly reversed IL-13-induced EMT and Z EB1 induction in CRC cells.
Journal ArticleDOI
Tumor-associated macrophages remodeling EMT and predicting survival in colorectal carcinoma.
Si Li,Fangying Xu,Jing Zhang,Lili Wang,Yang Zheng,Xuesong Wu,Jing Wang,Qiong Huang,Maode Lai +8 more
TL;DR: This study provided direct morphological evidence that tumor-associated macrophages in the invasive front play critical roles in fighting with the unfavorable results of tumor buds, thus resulting favorable outcomes for CRC patients.
Journal ArticleDOI
Cancer Stemness, Immune Cells, and Epithelial–Mesenchymal Transition Cooperatively Predict Prognosis in Colorectal Carcinoma
TL;DR: Investigating for the first time the clinical significance of combining cancer stem cells, immune cells, and EMT traits in colorectal cancer found them to be associated with each other, and cluster SIE was an independent predictor for 5‐year survival of patients with colore CT scans.
Journal ArticleDOI
Methylation status of ADAM12 promoter are associated with its expression levels in colorectal cancer.
TL;DR: In this paper, a systematic and comprehensive analysis of relationship of DNA hypermethylation and ADAM12 expression in colorectal cancer was performed in their samples and TCGA database.
Journal ArticleDOI
The expression of ADAMTS14 is regulated by promoter DNA methylation and is associated with poor prognosis in colorectal cancer.
TL;DR: Zhang et al. as discussed by the authors revealed that ADAMTS14 was highly methylated accompanied with low expression in colorectal cancer and demethylation agent 5-Aza-dC could demethylate ADAMS14 promoter region and reactivate ADCTS14 expression effectively in vitro.