Y
Yan Wang
Researcher at Zhejiang University
Publications - 4
Citations - 19
Yan Wang is an academic researcher from Zhejiang University. The author has contributed to research in topics: DNA methylation & Methylation. The author has an hindex of 2, co-authored 4 publications receiving 8 citations.
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Journal ArticleDOI
GLTSCR1 Negatively Regulates BRD4‐Dependent Transcription Elongation and Inhibits CRC Metastasis
Fengyan Han,Lei Zhang,Chaoyi Chen,Yan Wang,Yi Zhang,Lili Qian,Wenjie Sun,Dan Zhou,Beibei Yang,Honghe Zhang,Maode Lai,Maode Lai +11 more
TL;DR: This study highlights the molecular mechanism of the GLTSCR1‐BRD4 interaction, which is a potential therapeutic target for CRC and decreases sensitivity to bromodomain and extra terminal domain inhibitors.
Journal ArticleDOI
Methylation status of ADAM12 promoter are associated with its expression levels in colorectal cancer.
TL;DR: In this paper, a systematic and comprehensive analysis of relationship of DNA hypermethylation and ADAM12 expression in colorectal cancer was performed in their samples and TCGA database.
Journal ArticleDOI
The expression of ADAMTS14 is regulated by promoter DNA methylation and is associated with poor prognosis in colorectal cancer.
TL;DR: Zhang et al. as discussed by the authors revealed that ADAMTS14 was highly methylated accompanied with low expression in colorectal cancer and demethylation agent 5-Aza-dC could demethylate ADAMS14 promoter region and reactivate ADCTS14 expression effectively in vitro.