J
Jinhong Chen
Researcher at Tongji University
Publications - 1
Citations - 228
Jinhong Chen is an academic researcher from Tongji University. The author has contributed to research in topics: Cytotoxic T cell & CD8. The author has an hindex of 1, co-authored 1 publications receiving 171 citations.
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miR-424(322) reverses chemoresistance via T-cell immune response activation by blocking the PD-L1 immune checkpoint
Shaohua Xu,Zhen Tao,Bo Hai,Huagen Liang,Ying Shi,Tao Wang,Wen Song,Yong Chen,Jun OuYang,Jinhong Chen,Fanfei Kong,Yishan Dong,Shi Wen Jiang,Weiyong Li,Ping Wang,Zhiyong Yuan,Xiaoping Wan,Chenguang Wang,Wencheng Li,Xiaoping Zhang,Ke Chen +20 more
TL;DR: It is demonstrated that miR-424(322) regulates the PD-L1/PD-1 and CD80/CTLA-4 pathways in chemoresistant ovarian cancer, and data suggest a biological and functional interaction between PD- L1 and chemoresistance through the microRNA regulatory cascade.