Jinwei Ren

TL;DR: Pharmacological results showed that ganomycin I exerted potent and efficacious hypoglycemic, hypolipidemic, and insulin-sensitizing effects in KK-Ay mice.

TL;DR: Four new monoterpenoids and one new sesquiterpenoid were isolated from the mycelia of edible mushroom Pleurotus cornucopiae fermented on rice, showing moderate inhibitory activity against nitric oxide production in lipopolysaccaride-activated macrophages and cytotoxicity against HeLa and HepG2 cells.

TL;DR: The identification and verification of EriG, a member of the UbiA superfamily, is presented as the enzyme responsible for the cyclization of the cyathane skeleton in the mushroom Hericium erinaceum, leading to the discovery of a new family of ubiquitous UBiA-related diterpene cyclases in bacteria and fungi.

TL;DR: Three new nortriterpenes, ganoboninketals A-C (1-3), featuring rearranged 3,4-seco-27-norlanostane skeletons and highly complex polycyclic systems were isolated from the medicinal mushroom Ganoderma boninense.

TL;DR: Two new heterodimeric sesquiterpenes, sterhirsutins C (1) and D (2), along with eight new sesQUiterpenoid derivatives, sterHirsutin E--L (3-10), were isolated from the culture of Stereum hirsutum and possessed an unprecedented chemical skeleton with a 5/5/ 5/6/9/4 fused ring system.