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Jinyi Liu

Researcher at Third Military Medical University

Publications -  118
Citations -  2681

Jinyi Liu is an academic researcher from Third Military Medical University. The author has contributed to research in topics: DNA methylation & Lung cancer. The author has an hindex of 26, co-authored 101 publications receiving 2003 citations. Previous affiliations of Jinyi Liu include New York University & Chinese Ministry of Education.

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Epigenetic inactivation of LHX6 mediated microcystin-LR induced hepatocarcinogenesis via the Wnt/β-catenin and P53 signaling pathways

TL;DR: It is demonstrated for the first time that LHX6 gene expression is regulated by DNA methylation and can inhibit the proliferation, invasion and migration through Wnt/β-catenin and P53 signaling pathways during the MC-LR-induced hepatocarcinogenesis.
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High IGF2 expression is associated with poor clinical outcome in human ovarian cancer.

TL;DR: Evidence is provided that IGF2 expression is frequently increased in ovarian cancer tissues, and high expression of IGF2 may be a significant prognostic factor for poor survival in Ovarian cancer patients.
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Extremely Low-Frequency Electromagnetic Fields Affect the miRNA-Mediated Regulation of Signaling Pathways in the GC-2 Cell Line.

TL;DR: Go term and KEGG pathway annotation based on the miRNA expression profiling results showed that miRNAs may regulate circadian rhythms, cytokine-cytokine receptor interactions and the p53 signaling pathway.
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BPDE and B[a]P induce mitochondrial compromise by ROS-mediated suppression of the SIRT1/TERT/PGC-1α pathway in spermatogenic cells both in vitro and in vivo.

TL;DR: The results of the present study demonstrate that B[a]P and BPDE induce mitochondrial damage through ROS production that suppresses SIRT1/TERT/PGC-1a signaling and mediate B[ a]P- and B PDE-mediated reproductive toxicity.
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The effect of two cryopreservation methods on human sperm DNA damage.

TL;DR: It is concluded that storage of neat semen samples at -80 °C had milder damage to sperm DNA than storage at-196-°C mixed with cryoprotectants, and repeated freezing and thawing should be prevented to avoid additional sperm DNA damage.