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Jinyi Liu

Researcher at Third Military Medical University

Publications -  118
Citations -  2681

Jinyi Liu is an academic researcher from Third Military Medical University. The author has contributed to research in topics: DNA methylation & Lung cancer. The author has an hindex of 26, co-authored 101 publications receiving 2003 citations. Previous affiliations of Jinyi Liu include New York University & Chinese Ministry of Education.

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TC2N, a novel oncogene, accelerates tumor progression by suppressing p53 signaling pathway in lung cancer

TL;DR: A role for the p53 inactivator TC2N in regulating the proliferation and apoptosis of lung cancer cells is uncovered and novel insights into the mechanism of tumorigenesis in lung cancer are provided.
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Mechanisms of Stress-Induced Spermatogenesis Impairment in Male Rats Following Unpredictable Chronic Mild Stress (uCMS)

TL;DR: It is demonstrated for the first time that the activation of GR signaling mediates stress-induced spermatogenesis impairment and that this outcome is related to cell apoptosis and cell cycle arrest in germ cells.
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High expression of SOX30 is associated with favorable survival in human lung adenocarcinoma

TL;DR: SOX30 expression represents an important prognostic factor for survival time in ADC patients and is a favorable and independent prognostic factors in one main subtype of NSCLC, lung adenocarcinoma (ADC) patients.
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ALX4, an epigenetically down regulated tumor suppressor, inhibits breast cancer progression by interfering Wnt/β-catenin pathway.

TL;DR: It is revealed for the first time that ALX4 acts as a novel functional tumor suppressor inactivated by DNA methylation and is an independent prognostic factor in breast cancer patients.
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Aberrant methylation accounts for cell adhesion-related gene silencing during 3-methylcholanthrene and diethylnitrosamine induced multistep rat lung carcinogenesis associated with overexpression of DNA methyltransferases 1 and 3a.

TL;DR: It is suggested that DNMT1 and DNMT3a protein overexpression may be responsible for this aberrant DNA methylation and an accumulation of hypermethylation accounts for cell adhesion-related gene silencing is associated with dynamic changes in the progression of MCA/DEN-induced rat lung carcinogenesis.