J
Jinyoung Kim
Researcher at Dankook University
Publications - 39
Citations - 1137
Jinyoung Kim is an academic researcher from Dankook University. The author has contributed to research in topics: Conceptus & PI3K/AKT/mTOR pathway. The author has an hindex of 19, co-authored 39 publications receiving 982 citations. Previous affiliations of Jinyoung Kim include Texas A&M University & Seoul National University.
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Journal ArticleDOI
Select Nutrients in the Ovine Uterine Lumen. VII. Effects of Arginine, Leucine, Glutamine, and Glucose on Trophectoderm Cell Signaling, Proliferation, and Migration
Jinyoung Kim,Robert C. Burghardt,Guoyao Wu,Greg A. Johnson,Thomas E. Spencer,Fuller W. Bazer,Fuller W. Bazer +6 more
TL;DR: In this paper, the effects of arginine (Arg), leucine (Leu), glutamine (Gln), and glucose increase in the uterine lumen between days 10 and 15 of pregnancy, coincident with increases in expression of amino acid and glucose transporters by uterine epithelia as well as trophectoderm and yolk sac of conceptuses.
Journal ArticleDOI
Secreted phosphoprotein 1 binds integrins to initiate multiple cell signaling pathways, including FRAP1/mTOR, to support attachment and force-generated migration of trophectoderm cells
Jinyoung Kim,David W. Erikson,Robert C. Burghardt,Thomas E. Spencer,Guoyao Wu,Kayla J. Bayless,Greg A. Johnson,Fuller W. Bazer,Fuller W. Bazer +8 more
TL;DR: It is demonstrated that SPP1 binds alphavbeta3 and alpha5beta1 integrins to induce focal adhesion assembly, a prerequisite for adhesion and migration of Tr cells, through activation of: 1) P70S6K via crosstalk between FRAP1/mTOR and MAPK pathways; 2) mTOR, PI3K, MAPK3/MAPK1 (Erk1/2) and MAPk14 (p38) signaling
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Select Nutrients in the Ovine Uterine Lumen. VIII. Arginine Stimulates Proliferation of Ovine Trophectoderm Cells Through MTOR-RPS6K-RPS6 Signaling Cascade and Synthesis of Nitric Oxide and Polyamines
Jinyoung Kim,Robert C. Burghardt,Guoyao Wu,Greg A. Johnson,Thomas E. Spencer,Fuller W. Bazer +5 more
TL;DR: Results indicate that l-Arg enhances production of polyamines and NO and activates the MTOR/FRAP1-RPS6K- RPS6 signaling pathway to stimulate proliferation and migration of oTr cells.
Journal ArticleDOI
Select nutrients in the ovine uterine lumen. IX. Differential effects of arginine, leucine, glutamine, and glucose on interferon tau, ornithine decarboxylase, and nitric oxide synthase in the ovine conceptus.
Jinyoung Kim,Robert C. Burghardt,Guoyao Wu,Greg A. Johnson,Thomas E. Spencer,Fuller W. Bazer +5 more
TL;DR: Findings indicate that Arg, Leu, Gln, and glucose stimulate translation of mRNAs to increase synthesis of proteins through phosphorylation and activation of components of the MTOR signaling pathway.
Journal ArticleDOI
Insulin-like growth factor binding protein-1 in the ruminant uterus: potential endometrial marker and regulator of conceptus elongation.
Rebecca M. Simmons,David W. Erikson,Jinyoung Kim,Robert C. Burghardt,Fuller W. Bazer,Greg A. Johnson,Thomas E. Spencer +6 more
TL;DR: Investigation of temporal and spatial alterations in IGF binding protein (IGFBP)-1 and IGFBP3 in the ovine and bovine uterus reveals that IGFBP1 is a common endometrial marker of conceptus elongation in sheep and cattle and most likely regulates conceptus lengthening by stimulating migration and attachment of the trophectoderm.