J
Jinyoung Lee
Researcher at Purdue University
Publications - 10
Citations - 503
Jinyoung Lee is an academic researcher from Purdue University. The author has contributed to research in topics: Zebrafish & Genotoxicity. The author has an hindex of 9, co-authored 10 publications receiving 425 citations. Previous affiliations of Jinyoung Lee include Kyoto University & Seoul National University.
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Chronic exposure to diclofenac on two freshwater cladocerans and Japanese medaka.
TL;DR: Three-month exposure of fish to 0.001-10 mg/L of diclofenac resulted in significant decreasing trend in hatching success and delay in hatch, while fertility of the parent generation was not affected.
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Zebrafish as a model for investigating developmental lead (Pb) neurotoxicity as a risk factor in adult neurodegenerative disease: A mini-review
Jinyoung Lee,Jennifer L. Freeman +1 more
TL;DR: The zebrafish is being used in developmental Pb neurotoxicity studies to define genetic mechanisms of toxicity and associated neurobehavioral alterations and supports the potential for this in vivo model to further investigate the link between developmental P b exposure and adult neurodegenerative disease pathogenesis.
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Genotoxicity and Endocrine-Disruption Potentials of Sediment near an Oil Spill Site: Two Years after the Hebei Spirit Oil Spill
Kyunghee Ji,Jihyeon Seo,Xiaoshan Liu,Jinyoung Lee,Sangwoo Lee,Woojin Lee,Jeongim Park,Jong Seong Khim,Seongjin Hong,Yeyong Choi,Won Joon Shim,Shunichi Takeda,John P. Giesy,Kyungho Choi +13 more
TL;DR: The genotoxicicity and endocrine-disruption potential of the sediment extracts suggest a need for long-term followup for such toxicity in humans and wildlife in this area.
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Lead (Pb) exposure reduces global DNA methylation level by non-competitive inhibition and alteration of dnmt expression
Oscar F. Sánchez,Jinyoung Lee,Nathaphon Yu King Hing,Seong-Eun Kim,Jennifer L. Freeman,Chongli Yuan +5 more
TL;DR: In this article, the effects of low-dose exposure to lead (Pb) is connected to developmental neurological alterations by inducing molecular changes, such as aberrant gene expression patterns.
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A novel approach using DNA-repair-deficient chicken DT40 cell lines for screening and characterizing the genotoxicity of environmental contaminants
Kyunghee Ji,Kyunghee Ji,Toshiaki Kogame,Kyungho Choi,Xin Wang,Jinyoung Lee,Jinyoung Lee,Yoshihito Taniguchi,Shunichi Takeda +8 more
TL;DR: A novel bioassay employing gene-disrupted clones of the chicken DT40 B-lymphocyte line designed to be deficient in several specific DNA repair pathways is developed, which is a reliable and sensitive screening tool for environmental mutagens as well as for characterizing the nature of detected genotoxicity.