Jiri Jarkovsky

TL;DR: Among patients at high risk for stroke and increased risk of bleeding, LAAC was noninferior to DOAC in preventing major AF-related cardiovascular, neurological, and bleeding events.

TL;DR: No randomized head-to-head comparison of the efficacy and safety of ticagrelor and prasugrel has been published in the 7 years since the higher efficacy of these newer P2Y12 inhibitors w...

TL;DR: Among patients with refractory out-of-hospital cardiac arrest, the bundle of early intra-arrest transport, extracorporeal cardiopulmonary resuscitation, and invasive assessment and treatment did not significantly improve survival with neurologically favorable outcome at 180 days compared with standard resuscitation.

TL;DR: Invasive ventilation and age over 70 years were the most important predictive factors for mortality in both genders with or without cardiogenic shock, and low systolic blood pressure, low cholesterol level, hyponatremia, hyperkalemia, the use of inotropic agents and norepinephrine were predictive parameters for in-hospital mortality in patients without carduogenic shock.

TL;DR: Prasugrel and ticagrelor are similarly effective during the first year after MI and patients who were economically motivated to switch to clopidogrel had a lower risk of major cardiovascular events; however, they also had lower ischemic risk.