J
Jan Bělohlávek
Researcher at First Faculty of Medicine, Charles University in Prague
Publications - 123
Citations - 5637
Jan Bělohlávek is an academic researcher from First Faculty of Medicine, Charles University in Prague. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 12, co-authored 77 publications receiving 2474 citations. Previous affiliations of Jan Bělohlávek include University of Paris & Charles University in Prague.
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Journal ArticleDOI
Dapagliflozin in Patients with Heart Failure and Reduced Ejection Fraction
John J.V. McMurray,Scott D. Solomon,Silvio E. Inzucchi,Lars Køber,Mikhail Kosiborod,Felipe Martinez,Piotr Ponikowski,Marc S. Sabatine,Marc S. Sabatine,Inder S. Anand,Jan Bělohlávek,Michael Böhm,Chern-En Chiang,Chern-En Chiang,Vijay K. Chopra,Rudolf A. de Boer,Akshay S. Desai,Mirta Diez,Jarosław Drożdż,Andrej Dukát,Junbo Ge,Jonathan G. Howlett,Jonathan G. Howlett,Tzvetana Katova,Masafumi Kitakaze,Charlotta Ljungman,Béla Merkely,Jose C. Nicolau,Eileen O'Meara,Mark C. Petrie,Pham Nguyen Vinh,Morten Schou,Tereshchenko Sn,Subodh Verma,Claes Held,David L. DeMets,Kieran F. Docherty,Pardeep S. Jhund,Olof Bengtsson,Mikaela Sjöstrand,AM Langkilde +40 more
TL;DR: Among patients with heart failure and a reduced ejection fraction, the risk of worsening heart failure or death from cardiovascular causes was lower among those who received dapagliflozin than amongThose who received placebo, regardless of the presence or absence of diabetes.
Journal ArticleDOI
Hypothermia versus Normothermia after Out-of-Hospital Cardiac Arrest.
Josef Dankiewicz,Tobias Cronberg,Gisela Lilja,Janus Christian Jakobsen,Helena Levin,Susann Ullén,Christian Rylander,Matt P. Wise,Mauro Oddo,Alain Cariou,Jan Bělohlávek,Jan Hovdenes,Manoj Saxena,Hans Kirkegaard,Paul J Young,Paolo Pelosi,Christian Storm,Fabio Silvio Taccone,Michael Joannidis,Clifton W. Callaway,Glenn M Eastwood,Matt Morgan,Per Nordberg,David Erlinge,Alistair Nichol,Michelle S Chew,Jacob Hollenberg,Matthew L. Thomas,Jeremy Bewley,Katie Sweet,Anders Morten Grejs,Steffen Christensen,Matthias Haenggi,Anja Levis,Andreas Lundin,Joachim Düring,Simon Schmidbauer,Thomas R. Keeble,Grigoris V. Karamasis,Claudia Schrag,Edith Faessler,Ondrej Smid,Michal Otáhal,Marco Maggiorini,Pedro D. Wendel Garcia,Paul Jaubert,Jade M. Cole,Miroslav Solar,Ola Borgquist,Christoph Leithner,Samia Abed-Maillard,Leanlove Navarra,Martin Annborn,Johan Undén,Iole Brunetti,Akil Awad,Peter McGuigan,Roy Bjørkholt Olsen,Tiziano Cassina,Philippe Vignon,Halvor Langeland,Theis Lange,Hans Friberg,Niklas Nielsen +63 more
TL;DR: In this article, targeted temperature management is recommended for patients after cardiac arrest, but the supporting evidence is of low certainty, and an open-label trial with blinded asymptotics was conducted.
Journal ArticleDOI
Dapagliflozin in Heart Failure with Mildly Reduced or Preserved Ejection Fraction.
Scott D. Solomon,John J.V. McMurray,Brian Claggett,W. De Boer,David L. DeMets,Adrian F. Hernandez,Silvio E. Inzucchi,Mikhail Kosiborod,Carolyn S.P. Lam,Felipe Martinez,Akshay S. Desai,Pardeep S. Jhund,Jan Bělohlávek,Chern-En Chiang,C. Jan Willem Borleffs,Josep Comín-Colet,Dan Dobreanu,Jarosław Drożdż,James C. Fang,Marco Antonio Alcocer-Gamba,Waleed Al Habeeb,Yaling Han,Jose Walter Cabrera Honorio,Stefan Janssens,Tzvetana Katova,Masafumi Kitakaze,Béla Merkely,Eileen O'Meara,José Francisco Kerr Saraiva,S. N. Tereshchenko,Jorge Thierer,Muthiah Vaduganathan,Orly Vardeny,Subodh Verma,Vinh N. Pham,Ulrica Wilderäng,Natalia Zaozerska,Erasmus Bachus,Dan Lindholm,Magnus Petersson,Anna Maria Langkilde +40 more
TL;DR: Dapagliflozin reduced the combined risk of worsening heart failure or cardiovascular death among patients with heart failure and a mildly reduced or preserved ejection fraction and results were similar in prespecified subgroups, including patients with or without diabetes.
Journal ArticleDOI
Effect of Intra-arrest Transport, Extracorporeal Cardiopulmonary Resuscitation, and Immediate Invasive Assessment and Treatment on Functional Neurologic Outcome in Refractory Out-of-Hospital Cardiac Arrest: A Randomized Clinical Trial.
Jan Bělohlávek,J. Šmalcová,D. Rob,O. Franěk,Ondrej Smid,Milana Pokorna,Jan Horák,Vratislav Mrazek,Tomas Kovarnik,David Zemánek,Ales Kral,Stepan Havranek,P Kaválková,Lucie Kompelentova,Helena Tomková,Alan Mejstrik,Jaroslav Valasek,David Peran,Jaroslav Pekara,Jan Rulisek,Martin Balik,Michal Huptych,Jiri Jarkovsky,Jan Malik,Anna Valerianova,Frantisek Mlejnsky,Petr Kolouch,Petra Havránková,D. Romportl,Arnošt Komárek,Aleš Linhart +30 more
TL;DR: Among patients with refractory out-of-hospital cardiac arrest, the bundle of early intra-arrest transport, extracorporeal cardiopulmonary resuscitation, and invasive assessment and treatment did not significantly improve survival with neurologically favorable outcome at 180 days compared with standard resuscitation.
Journal ArticleDOI
Primary angioplasty in acute myocardial infarction with right bundle branch block: should new onset right bundle branch block be added to future guidelines as an indication for reperfusion therapy?
Petr Widimsky,Filip Rohac,Josef Stasek,Petr Kala,Richard Rokyta,Boyko Kuzmanov,Martin Jakl,Martin Poloczek,Jan Kaňovský,Ivo Bernat,Ota Hlinomaz,Jan Bělohlávek,Ales Kral,Vratislav Mrazek,Vladimir Grigorov,Slaveyko N Djambazov,Robert Petr,Jiri Knot,Dana Bilkova,Michaela Fischerova,Karel Vondrak,Marek Malý,Alena Lorencová +22 more
TL;DR: Acute myocardial infarction with RBBB is frequently caused by the complete occlusion of the infarct-related artery and is more frequently treated with primary PCI when compared with AMI + LBBB.