다중혈관 관상동맥 환자에서 y-문합을 이용하여 양쪽 내흉동맥만을 사용한 우회술의 조기 성적

Fibre lasers in the mid-infrared regime are useful for a diverse range of fields, including chemical and biomedical sensing, military applications and materials processing. This Review summarizes the different rare-earth cations and host materials used in mid-infrared fibre laser technology, and discusses the future applications and challenges for the field.

Towards high-power mid-infrared emission from a fibre laser

Infrared (2–12 μm) solid-state laser sources: a review

Fiber lasers have seen progressive developments in terms of spectral coverage and linewidth, output power, pulse energy, and ultrashort pulse width since the first demonstration of a glass fiber laser in 1964. Their applications have extended into a variety of fields accordingly. In this paper, the milestones of glass fiber laser development are briefly reviewed and recent advances of high-power continuous wave, Q-switched, mode-locked, and single-frequency fiber lasers in the 1, 1.5, 2, and 3 μm regions and their applications in such areas as industry, medicine, research, defense, and security are addressed in detail.

Fiber lasers and their applications [Invited]

In this review we discuss the application of laser-induced breakdown spectroscopy (LIBS) to the problem of detection of residues of explosives. Research in this area presented in open literature is reviewed. Both laboratory and field-tested standoff LIBS instruments have been used to detect explosive materials. Recent advances in instrumentation and data analysis techniques are discussed, including the use of double-pulse LIBS to reduce air entrainment in the analytical plasma and the application of advanced chemometric techniques such as partial least-squares discriminant analysis to discriminate between residues of explosives and non-explosives on various surfaces. A number of challenges associated with detection of explosives residues using LIBS have been identified, along with their possible solutions. Several groups have investigated methods for improving the sensitivity and selectivity of LIBS for detection of explosives, including the use of femtosecond-pulse lasers, supplemental enhancement of the laser-induced plasma emission, and complementary orthogonal techniques. Despite the associated challenges, researchers have demonstrated the tremendous potential of LIBS for real-time detection of explosives residues at standoff distances.

Laser-induced breakdown spectroscopy for detection of explosives residues: a review of recent advances, challenges, and future prospects

A concept is explored for combining the Doppler and DIAL techniques into a single, multifunctional instrument. Wind, CO2 concentration, and aerosol density can all be measured. Technology to build this instrument is described, including the demonstration of a prototype lidar. Applications are described for use in the Earth science. The atmosphere of Mars can also be studied, and results from a recently-developed simulation model of performance in the Martian atmosphere are presented.

/pdf/combined-2-micron-dial-and-doppler-lidar-application-to-the-z7r7iccrme.pdf

Combined 2-micron Dial and Doppler Lidar: Application to the Atmosphere of Earth or Mars

This study aimed to investigate the effect of curcumin (Cur) against human cytomegalovirus (HCMV) in vitro. Human embryonic lung fibroblasts were cultured in vitro. The tetrazolium salt (MTS) method was used to detect the effects of Cur on cell viability. The cells were divided into control group, HCMV group, HCMV + (PFA) group and HCMV + Cur group in this study. The cytopathic effect (CPE) of each group was observed by plaque test, then the copy number of HCMV DNA in each group was detected by quantitative polymerase chain reaction (qPCR), and the expression of HCMV proteins in different sequence was detected by Western blot. The results showed that when the concentration of Cur was not higher than 15 μmol/L, there was no significant change in cell growth and viability in the Cur group compared with the control group (P>0.05). After the cells were infected by HCMV for 5 d, the cells began to show CPE, and the number of plaques increased with time. Pretreatment with Cur significantly reduced CPE in a dose-dependent manner. After the cells were infected by HCMV, the DNA copy number and protein expression gradually increased in a time-dependent manner. Pretreatment with Cur significantly inhibited HCMV DNA copies and downregulate HCMV protein expression levels in a concentration-dependent manner, and the difference was statistically significant (P<0.05). In conclusion, Cur may exert anti-HCMV activity by inhibiting the replication of HCMV DNA and down-regulating the expression levels of different sequence proteins of HCMV. This study provides a new experimental basis for the development of anti-HCMV infectious drugs.

[Activity of curcumin against human cytomegalovirus infection in vitro].

High-accuracy, vertical profiles of the horizontal vector wind in earth s atmosphere, with the global coverage of an orbiting sensor, are a highly desired measurement of NASA, NOAA, and many other agencies and countries. It is the consensus of NASA and NOAA that the most cost effective, lowest risk measurement method with the earliest achievable mission date is the hybrid Doppler lidar method which utilizes both coherent- and direct-detection Doppler lidars to obtain the desired profiles. NASA Langley Research Center (LaRC) has advanced the 2-micron pulsed solid-state laser greatly over the past 15 years and has recently demonstrated 1.2 J of pulse energy whereas the requirement for a 400-km hybrid Doppler lidar mission is only 0.25 J. The IIP project reported here is an effort to increase the ruggedness and to compactly package the LaRC state-of-the-art laser technology.

/pdf/compact-and-rugged-transceiver-for-coherent-doppler-wind-3fvr97qwxx.pdf

Compact and Rugged Transceiver for Coherent Doppler Wind Lidar Applications in Space

The design of a diode pumped, injection seeded MOPA with a transform limited line width and diffraction limited beam quality is presented. This lidar transmitter produces over 300mJ energy at 10 Hz repetition rate.

2.5 MHz line-width high-energy, 2 μm coherent wind Lidar transmitter Mulugeta Petrosa

We report on remote sensing measurements of atmospheric carbon dioxide by a double pulsed 2-micron coherent differential absorption lidar technique.

Jirong Yu

Papers

Combined 2-micron Dial and Doppler Lidar: Application to the Atmosphere of Earth or Mars

[Activity of curcumin against human cytomegalovirus infection in vitro].

Compact and Rugged Transceiver for Coherent Doppler Wind Lidar Applications in Space

2.5 MHz line-width high-energy, 2 μm coherent wind Lidar transmitter Mulugeta Petrosa

A Pulsed 2-micron Coherent Differential Absorption Lidar for Atmospheric CO2 Measurements