J
Jisnuson Svasti
Researcher at Chulabhorn Research Institute
Publications - 276
Citations - 5498
Jisnuson Svasti is an academic researcher from Chulabhorn Research Institute. The author has contributed to research in topics: Cancer & Cancer cell. The author has an hindex of 40, co-authored 255 publications receiving 4719 citations. Previous affiliations of Jisnuson Svasti include University of Mainz & Victoria University of Wellington.
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Journal ArticleDOI
Antiviral isoflavonoid sulfate and steroidal glycosides from the fruits of Solanum torvum.
Damrongkiet Arthan,Jisnuson Svasti,Prasat Kittakoop,Daraporn Pittayakhachonwut,Morakot Tanticharoen,Yodhathai Thebtaranonth,Yodhathai Thebtaranonth +6 more
TL;DR: Torvanol A (1), torvoside H (3) and compound 5 exhibited antiviral activity (herpes simplex virus type 1) with IC(50) values of 9.6, 23.2 and 17.4 microg/ml, respectively.
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Vanillin suppresses in vitro invasion and in vivo metastasis of mouse breast cancer cells
Kriengsak Lirdprapamongkol,Hiroaki Sakurai,Noritaka Kawasaki,Min-Kyung Choo,Yurika Saitoh,Yasushi Aozuka,Pattama Singhirunnusorn,Somsak Ruchirawat,Jisnuson Svasti,Jisnuson Svasti,Ikuo Saiki +10 more
TL;DR: The findings suggest that vanillin has anti-metastatic potential by decreasing invasiveness of cancer cells and may be of value in the development of anti- Metastatic drugs for cancer treatment.
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Vanillin suppresses metastatic potential of human cancer cells through PI3K inhibition and decreases angiogenesis in vivo.
Kriengsak Lirdprapamongkol,Jan-Peter Kramb,Tuangporn Suthiphongchai,Rudee Surarit,Chantragan Srisomsap,Gerd Dannhardt,Jisnuson Svasti +6 more
TL;DR: Vanillin and apocynin could inhibit the enzymatic activity of phosphoinositide 3-kinase (PI3K), suggesting that inhibition of PI3K activity was a mechanism underlying the inhibitory effect on cancer cell migration, and the presence of an aldehyde or ketone group in the vanillin structure was important for this inhibition.
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Mucoadhesive curcumin nanospheres: Biological activity, adhesion to stomach mucosa and release of curcumin into the circulation
Natthakitta Suwannateep,Wijit Banlunara,Supason Wanichwecharungruang,Khajeelak Chiablaem,Khajeelak Chiablaem,Kriengsak Lirdprapamongkol,Jisnuson Svasti,Jisnuson Svasti +7 more
TL;DR: Two monopolymeric carrier and a dipolymeric carrier made from a blend of methylcellulose and EC yielded the highest reported curcumin loading and showed an in vitro free radical scavenging activity and a dose-dependent in vitro cytotoxic effect towards MCF-7 human breast adenocarcinoma and HepG2 hepatoblastoma cells in tissue culture.
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Lupeol and stigmasterol suppress tumor angiogenesis and inhibit cholangiocarcinoma growth in mice via downregulation of tumor necrosis factor-α.
Thaned Kangsamaksin,Supattra Chaithongyot,Chanida Wootthichairangsan,Rattanavinan Hanchaina,Chayada Tangshewinsirikul,Jisnuson Svasti,Jisnuson Svasti +6 more
TL;DR: The findings indicate that lupeol and stigmasterol effectively target tumor endothelial cells and suppress CCA tumor growth by their anti-inflammatory activities and are attractive candidates for anti-cancer treatment of CCA tumors.