Jitka Cejkova

TL;DR: The results show that trehalose accelerated healing of the UVB irradiated cornea, very probably via suppression of hypoxia-response injury, and immunohistochemical results on corneal cryostat sections corresponded with those obtained using corNEal impression cytologies, thus confirming that corneale impression cytology are useful for diagnostic purposes.

TL;DR: This study reveals the cumulative effect of repeated UVB irradiations, and shows that even a 48-hour interval between subsequent UVR-B exposures is not sufficient for the healing processes to restore lenticular integrity.

TL;DR: Investigating whether trehalose might decrease the damage of the rabbit cornea evoked by UVB rays found it reduced UVB-induced damage caused by reactive oxygen and nitrogen species and decreased changes in the corneal optics.

TL;DR: Evidence is provided that the developed trehalose medium can be applied as a low-cost and efficient solution for the hypothermic storage of MSC suspensions, with a high potential for translation into clinical practice.

TL;DR: It is suggested that xanthine oxidase is involved in the generation of ROS in the anterior eye segment during early irradiation of the eyes with UVB rays and participates in its damage.